Hiraiwa K, Shinjo T
Nihon Juigaku Zasshi. 1989 Dec;51(6):1111-4. doi: 10.1292/jvms1939.51.1111.
Three strains of Fusobacterium necrophorum biovar C were injected into mice intraperitoneally and intraportally. All the mice survived. In one mouse out of 15 mice injected intraperitoneally, a few focal abscesses were formed in the liver. The microorganisms were recovered from the liver abscess and the tissue of liver with abscess. No changes were observed in the organs of other 14 mice and no bacteria were recovered from them. In the 15 mice injected intraportally, no liver abscesses and no macroscopic changes in the organs were formed. However, the inoculated bacteria were recovered from the liver of four mice. The pathogenicity of F. necrophorum biovar C was weaker than that of other two biovars.
将三株坏死梭杆菌生物变种C分别经腹腔和门静脉注射到小鼠体内。所有小鼠均存活。在15只经腹腔注射的小鼠中,有1只小鼠的肝脏形成了一些局灶性脓肿。从肝脓肿和有脓肿的肝脏组织中分离出了微生物。其他14只小鼠的器官未观察到变化,也未从中分离出细菌。在15只经门静脉注射的小鼠中,未形成肝脓肿,器官也未出现宏观变化。然而,从4只小鼠的肝脏中分离出了接种的细菌。坏死梭杆菌生物变种C的致病性比其他两个生物变种弱。