5q-贫血克隆进化的细胞遗传学证据。
Cytogenetic evidence of clonal evolution in 5q- anemia.
作者信息
Verhest A, Lustman F, Wittek M, van Schoubroeck F, Naets J P
出版信息
Biomedicine. 1977 Jul;27(6):211-2.
PMID:268980
Abstract
The clinical homogeneity of myeloproliferative syndromes associated with a 5 q- marker can be contested, but nevertheless finds support in the 2 case reports we have cited. One of these observations of refractory anemia with partial myeloblastosis and 5 q- marker has shown a transformation into an acute myelomonocytic leukemia with clonal chromosomal evolution.
摘要
与5号染色体长臂缺失标记相关的骨髓增殖性综合征的临床同质性可能存在争议，但尽管如此，在我们引用的2例病例报告中还是得到了支持。其中1例难治性贫血伴部分原始粒细胞增多症及5号染色体长臂缺失标记的观察显示，其已转变为具有克隆性染色体演变的急性粒单核细胞白血病。
Zotero 插件