Ersoy Burak, Sahin Ersoy Gulcin
Maltepe University School of Medicine, Department of Plastic, Reconstructive and Aesthetic Surgery, Istanbul, Turkey.
Kartal Dr. Lutfi Kirdar Education and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
Burns. 2016 Jun;42(4):949-50. doi: 10.1016/j.burns.2016.01.029. Epub 2016 Feb 15.
Skin graft studies in rats constitute a valuable adjunct to scientific human experimentations, however the harvesting of split thickness skin graft poses a challenge to the researcher due to the presence of panniculus carnosus tissue in rat skin. This striated muscle tissue renders significant laxity and mobility to the skin layer, greatly interfering with the process of skin graft harvest. In order to fixate the rat skin and limit its flexibility various techniques and modifications have been described, which mostly rely on the use of subdermal implanted templates. These methods are therefore time consuming, with an additional exposure to surgical stress and wounds. A new and simple technique is presented which offers a rapid and reliable alternative to the existing methods of split thickness skin graft harvesting without any additional invasive procedure or extra instruments other than the researchers hands and a dermatome.
大鼠皮肤移植研究是人体科学实验的重要辅助手段，然而，由于大鼠皮肤中存在肉膜组织，获取中厚皮片对研究人员来说是一项挑战。这种横纹肌组织使皮肤层具有显著的松弛度和活动性，极大地干扰了皮肤移植的获取过程。为了固定大鼠皮肤并限制其灵活性，人们描述了各种技术和改进方法，这些方法大多依赖于皮下植入模板的使用。因此，这些方法耗时较长，且会使大鼠额外承受手术压力和伤口。本文介绍了一种新的简单技术，它为现有的中厚皮片获取方法提供了一种快速可靠的替代方案，除了研究人员的双手和取皮刀外，无需任何额外的侵入性操作或额外器械。
