Krause Kay J, Adly Nouran, Yakushenko Alexey, Schnitker Jan, Mayer Dirk, Offenhäusser Andreas, Wolfrum Bernhard
Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.
Neuroelectronics, IMETUM, Department of Electrical and Computer Engineering, Technical University of Munich (TUM) , Boltzmannstrasse 11, 85748 Garching, Germany.
Anal Chem. 2016 Apr 5;88(7):3632-7. doi: 10.1021/acs.analchem.5b04306. Epub 2016 Mar 8.
We investigate the influence of self-assembled alkanethiol monolayers at the surface of platinum microelectrode arrays on the stochastic amperometric detection of citrate-stabilized silver nanoparticles in aqueous solutions. The measurements were performed using a microelectrode array featuring 64 individually addressable electrodes that are recorded in parallel with a sampling rate of 10 kHz for each channel. We show that both the functional end group and the total length of the alkanethiol influence the charge transfer. Three different terminal groups, an amino, a hydroxyl, and a carboxyl, were investigated using two different molecule lengths of 6 and 11 carbon atoms. Finally, we show that a monolayer of alkanethiols with a length of 11 carbon atoms and a carboxyl terminal group can efficiently block the charge transfer of free nanoparticles in an aqueous solution.
我们研究了铂微电极阵列表面自组装的烷硫醇单分子层对水溶液中柠檬酸盐稳定的银纳米颗粒随机安培检测的影响。测量使用了一个具有64个可单独寻址电极的微电极阵列，每个通道以10 kHz的采样率并行记录。我们表明，烷硫醇的官能端基和总长度都会影响电荷转移。使用两种不同碳原子长度（6和11）研究了三种不同的端基，即氨基、羟基和羧基。最后，我们表明，具有11个碳原子长度和羧基端基的烷硫醇单分子层可以有效阻断水溶液中游离纳米颗粒的电荷转移。
