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Therapeutic Potential of Neuregulin in Cardiovascular System: Can we Ignore the Effects of Neuregulin on Electrophysiology?

作者信息

Wang Xi, Liu Zhiqiang, Duan Hui Nan, Wang Long

机构信息

Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan, China.

Cardiovascular Research Institute, Wuhan University, Wuhan, China, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China.

出版信息

Mini Rev Med Chem. 2016;16(11):867-71. doi: 10.2174/1389557516666160223122039.

DOI:10.2174/1389557516666160223122039
PMID:26902151
Abstract

Neuregulin-1(NRG-1) has now been accepted to have therapeutic potential in cardiovascular disease. The preclinical and clinical researches of NRG-1 have demonstrated its advantage effects in cardiac function with multi-target cardiovascular biology and pathophysiology, but its influence on cardiac electrophysiology is rarely involved, which is a very important aspect and should not be ignored.

摘要

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Therapeutic Potential of Neuregulin in Cardiovascular System: Can we Ignore the Effects of Neuregulin on Electrophysiology?
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Mol Med Rep. 2020 Jun;21(6):2311-2320. doi: 10.3892/mmr.2020.11034. Epub 2020 Mar 20.
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Pretreatment with neuregulin-1 improves cardiac electrophysiological properties in a rat model of myocardial infarction.
在心肌梗死大鼠模型中,用神经调节蛋白-1进行预处理可改善心脏电生理特性。
Exp Ther Med. 2019 Apr;17(4):3141-3149. doi: 10.3892/etm.2019.7306. Epub 2019 Feb 25.