Therapeutic Potential of Neuregulin in Cardiovascular System: Can we Ignore the Effects of Neuregulin on Electrophysiology?

作者信息

Wang Xi, Liu Zhiqiang, Duan Hui Nan, Wang Long

机构信息

Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan, China.

Cardiovascular Research Institute, Wuhan University, Wuhan, China, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China.

出版信息

Mini Rev Med Chem. 2016;16(11):867-71. doi: 10.2174/1389557516666160223122039.

Neuregulin-1(NRG-1) has now been accepted to have therapeutic potential in cardiovascular disease. The preclinical and clinical researches of NRG-1 have demonstrated its advantage effects in cardiac function with multi-target cardiovascular biology and pathophysiology, but its influence on cardiac electrophysiology is rarely involved, which is a very important aspect and should not be ignored.