Hoffmann Federico G, McGuire Liam P, Counterman Brian A, Ray David A
Department of Biochemistry, Molecular Biology, Entomology and Plant Pathology; Mississippi State University; Mississippi State, MS USA; Institute for Genomics, Biocomputing, and Biotechnology; Mississippi State University; Mississippi State, MS USA.
Department of Biological Sciences; Texas Tech University ; Lubbock, TX USA.
Mob Genet Elements. 2015 Jul 24;5(5):63-66. doi: 10.1080/2159256X.2015.1066919. eCollection 2015 Sep-Oct.
While transposable elements (TE) have long been suspected of involvement in species diversification, identifying specific roles has been difficult. We recently found evidence of TE-derived regulatory RNAs in a species-rich family of bats. The TE-derived small RNAs are temporally associated with the burst of species diversification, suggesting that they may have been involved in the processes that led to the diversification. In this commentary, we expand on the ideas that were briefly touched upon in that manuscript. Specifically, we suggest avenues of research that may help to identify the roles that TEs may play in perturbing regulatory pathways. Such research endeavors may serve to inform evolutionary biologists of the ways that TEs have influenced the genomic and taxonomic diversity around us.
虽然转座元件(TE)长期以来一直被怀疑参与物种多样化,但确定其具体作用却很困难。我们最近在一个物种丰富的蝙蝠家族中发现了源自转座元件的调控RNA的证据。源自转座元件的小RNA在时间上与物种多样化的爆发相关联,这表明它们可能参与了导致多样化的过程。在这篇评论中,我们扩展了在那篇手稿中简要提及的观点。具体而言,我们提出了一些研究途径,这些途径可能有助于确定转座元件在干扰调控途径中可能发挥的作用。此类研究工作可能有助于让进化生物学家了解转座元件影响我们周围基因组和分类多样性的方式。