Dusza L
Institute of Animal Physiology, School of Agriculture and Technology, Olsztyn.
Acta Physiol Pol. 1989 Jan-Feb;40(1):74-84.
This review summarizes evidence that prolactin (PRL) is involved directly in the regulation of ovarian steroidogenesis. The scope of this paper will be limited to two areas. The first area involves the regulation of the corpus luteum function and the second the effect of PRL on steroidogenesis during the follicular phase of the oestrous cycle. Cyclic changes of plasma PRL levels and the ovarian receptors which bind PRL have been observed during the oestrous cycle of domestic animals. The luteotropic effect of PRL and its failure is also presented. PRL may exert a physiological effect on follicle steroidogenesis but its effect depends on the level of follicle maturation. The effect of PRL treatment on estrogen production by follicular cells in vivo and in vitro was studied. The results of many papers indicate suppression of estrogen secretion by the direct action of PRL at the ovarian level. However, there is abundant evidence, that PRL is involved directly in regulation of ovarian steroidogenesis, the precise mechanism remains to be discovered.
本综述总结了催乳素（PRL）直接参与卵巢类固醇生成调节的证据。本文的范围将限于两个领域。第一个领域涉及黄体功能的调节，第二个领域是PRL在发情周期卵泡期对类固醇生成的影响。在家畜发情周期中观察到血浆PRL水平和结合PRL的卵巢受体的周期性变化。还介绍了PRL的促黄体作用及其失效情况。PRL可能对卵泡类固醇生成产生生理影响，但其作用取决于卵泡成熟水平。研究了PRL处理对体内外卵泡细胞雌激素产生的影响。许多论文的结果表明，PRL在卵巢水平的直接作用会抑制雌激素分泌。然而，有大量证据表明PRL直接参与卵巢类固醇生成的调节，但其确切机制仍有待发现。
