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[系统性红斑狼疮中的心脏瓣膜受累。附2例报告并文献复习]

[Heart valve involvement in lupus erythematosus disseminatus. Apropos of 2 cases. Review of the literature].

作者信息

de Groote P, Tison E, Millaire A, Marquand A, Ducloux G

机构信息

Service de Cardiologie C, Hôpital Cardiologique, Lille.

出版信息

Ann Cardiol Angeiol (Paris). 1989 Nov;38(9):539-44.

PMID:2690725
Abstract

Regarding two cases of idiopathic lupus valvulopathy, the authors review the various mechanisms responsible for the endocardial lesions in disseminated lupus erythematosus. In addition to the classic Libman-Sachs endocarditis, there are sclerous forms, ruptures of the chords, thromboses and bacterial superinfections. The role of steroid therapy in the genesis of valvular stenosis is not always determined. A surgical treatment, effective and without major risk, must be advocated at an early stage in the presence of poorly tolerated forms.

摘要

关于两例特发性狼疮性瓣膜病,作者回顾了播散性红斑狼疮中心内膜病变的各种发病机制。除了典型的Libman-Sachs心内膜炎外,还有硬化形式、腱索破裂、血栓形成和细菌重叠感染。类固醇疗法在瓣膜狭窄发生过程中的作用并不总是明确的。对于耐受性差的病例,必须在早期提倡进行有效且风险不大的手术治疗。

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