Morbieu Caroline, Michel Pierre-Antoine, Brocheriou Isabelle, Canestri Ana, Boffa Jean-Jacques
Service de néphrologie et dialyses, hôpital Tenon, 4, rue de la Chine, 75970 Paris cedex 20, France.
Service de néphrologie et dialyses, hôpital Tenon, 4, rue de la Chine, 75970 Paris cedex 20, France.
Nephrol Ther. 2016 Jul;12(4):229-33. doi: 10.1016/j.nephro.2015.12.003. Epub 2016 Feb 19.
A 27-year-old man without any medical history presented concomitantly a pulmonary and urinary tuberculosis and a nephrotic syndrome with hematuria and renal failure. The renal biopsy showed increased mesangial matrix, few focal segmental lesions, and IgA deposits confirming the diagnosis of IgA nephropathy. Nephrotic syndrome remission occurred quickly after antituberculous treatment. The association between tuberculosis and IgA nephropathy has been previously reported in 9 patients. Renal outcome was always favorable with antituberculous treatment. No relapse occurred, with a maximal follow-up of 42 months. Here, we discuss this singular association and previous similar cases.
一名27岁无任何病史的男性同时出现肺结核和肾结核以及伴有血尿和肾衰竭的肾病综合征。肾活检显示系膜基质增加、少量局灶节段性病变以及IgA沉积，确诊为IgA肾病。抗结核治疗后肾病综合征迅速缓解。此前已有9例患者报告过结核病与IgA肾病之间的关联。抗结核治疗后肾脏预后总体良好。最长随访42个月，无复发情况。在此，我们讨论这种特殊关联及既往类似病例。
