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经胸超声心动图在认证胸痛单元中的应用:来自德国胸痛单元注册研究的结果。

The Use of Echocardiography in Certified Chest Pain Units: Results from the German Chest Pain Unit Registry.

作者信息

Breuckmann Frank, Hochadel Matthias, Voigtländer Thomas, Haude Michael, Schmitt Claus, Münzel Thomas, Giannitsis Evangelos, Mudra Harald, Heusch Gerd, Schumacher Burghard, Barth Sebastian, Schuler Gerhard, Hailer Birgit, Walther Dirk, Senges Jochen

机构信息

Department of Cardiology, Arnsberg Medical Center, Arnsberg, Germany.

出版信息

Cardiology. 2016;134(2):75-83. doi: 10.1159/000443475. Epub 2016 Feb 25.

Abstract

OBJECTIVES

To analyze the current usage of transthoracic echocardiography (TTE) as a rapid, noninvasive tool in the early stratification of acute chest pain in certified German chest pain units (CPUs).

METHODS

A total of 23,997 patients were enrolled. Analyses comprised TTE evaluation rates in relation to clinical presentation, risk profile, left ventricular impairment, final diagnosis and invasive management. Critical times were assessed. Multivariable analyses for independent determinants for the use of TTE were performed.

RESULTS

TTE evaluation was available in CPUs in 70.1% of cases. It was associated with lower rates of invasive management in unstable angina pectoris (UAP) and with higher rates in patients with initially suspected non-cardiac origin of symptoms and/or reduced systolic function (p < 0.05). Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) was an independent determinant favoring TTE evaluation [NSTE-myocardial infarction: odds ratio (OR) 1.62; UAP: OR 1.34; p < 0.001 for both]. Clinical signs of heart failure (OR 1.31; p < 0.001), referral by emergency medical service (OR 1.18; p < 0.001) and kidney failure (OR 1.16; p < 0.05) were independently associated with higher TTE rates. TTE did not delay door-to-balloon times.

CONCLUSIONS

About two thirds of the patients admitted to certified CPUs received TTE evaluation, with the highest rates being in ACS patients, and thereby providing diagnostic information supporting or refuting further invasive management.

摘要

目的

分析经胸超声心动图(TTE)作为一种快速、无创工具在德国认证胸痛中心(CPU)对急性胸痛进行早期分层中的当前应用情况。

方法

共纳入23997例患者。分析内容包括与临床表现、风险特征、左心室功能损害、最终诊断及侵入性治疗相关的TTE评估率。评估关键时间点。对TTE使用的独立决定因素进行多变量分析。

结果

70.1%的病例在CPU中可进行TTE评估。在不稳定型心绞痛(UAP)中,TTE评估与较低的侵入性治疗率相关,而在最初怀疑症状非心脏源性和/或收缩功能降低的患者中,TTE评估率较高(p<0.05)。非ST段抬高型急性冠状动脉综合征(NSTE-ACS)是有利于TTE评估的独立决定因素[NSTE-心肌梗死:比值比(OR)1.62;UAP:OR 1.34;两者p<0.001]。心力衰竭的临床体征(OR 1.31;p<0.001)、由紧急医疗服务机构转诊(OR 1.18;p<0.001)和肾衰竭(OR 1.16;p<0.05)与较高的TTE评估率独立相关。TTE并未延迟门球时间。

结论

在认证CPU入院的患者中,约三分之二接受了TTE评估,急性冠状动脉综合征(ACS)患者的评估率最高,从而提供了支持或反驳进一步侵入性治疗的诊断信息。

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