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索马里和埃塞俄比亚的肿瘤性钙化症:21例报告及文献简要综述

Tumoral calcinosis in Somalia and Ethiopia: a report of twenty one cases and brief review of literature.

作者信息

Jain S P

出版信息

East Afr Med J. 1989 Jul;66(7):476-80.

PMID:2691230
Abstract

Tumoral calcinosis is an uncommon lesion of obscure aetiology often misdiagnosed. It occurs predominantly in the Negroid and African races, but there is paucity of African literature. This is the first report of eleven cases amongst Somalis and ten Ethiopians, involving only the greater trochanteric, gluteal and iliac crest regions. The clinical, radiological, macroscopical and histological features are typical and universally similar. It may grow rapidly, but usually, gradually over the years, more frequently at the pressure points. Multiple tumours do occur; affects both the sexes and all ages, but here all the Somalis were females. Most cases in both the countries were elderly (60 to 75 years of age) in contrast to other series. Wide surgical excision is essential to avoid recurrence.

摘要

肿瘤性钙化是一种病因不明的罕见病变,常被误诊。它主要发生在黑人及非洲种族中,但非洲文献较少。这是关于11例索马里人和10例埃塞俄比亚人的首例报告,病变仅累及大转子、臀区和髂嵴区域。其临床、放射学、大体和组织学特征典型且普遍相似。它可能生长迅速,但通常多年来逐渐生长,更常见于受压部位。确实会出现多发性肿瘤;男女老少均可发病,但这里所有索马里患者均为女性。与其他系列研究相比,这两个国家的大多数病例为老年人(60至75岁)。广泛手术切除对于避免复发至关重要。

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Tumoral calcinosis in Somalia and Ethiopia: a report of twenty one cases and brief review of literature.索马里和埃塞俄比亚的肿瘤性钙化症:21例报告及文献简要综述
East Afr Med J. 1989 Jul;66(7):476-80.
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Hyperphosphatemic familial tumoral calcinosis caused by a mutation in GALNT3 in a European kindred.欧洲一个家族中由GALNT3基因突变引起的高磷血症性家族性肿瘤性钙化症。
J Hum Genet. 2006;51(5):487-490. doi: 10.1007/s10038-006-0377-6. Epub 2006 Mar 10.
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Tumoral Calcinosis in Infancy. A light and electron microscopic study with X-ray microanalysis.婴儿期肿瘤性钙化。一项结合X射线微量分析的光镜和电镜研究。
Pathol Oncol Res. 1995;1(1):80-84. doi: 10.1007/BF02893589.