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在预防深部胸骨伤口感染方面,胸骨缆线并不优于传统的胸骨钢丝固定。

Sternal cables are not superior to traditional sternal wiring for preventing deep sternal wound infection.

作者信息

Dunne Ben, Murphy Mark, Skiba Rohen, Wang Xiao, Ho Kwok, Larbalestier Robert, Merry Christopher

机构信息

Department of Cardiothoracic Surgery, Western Australian Cardiothoracic Research and Audit Group, Fiona Stanley Hospital, Perth, WA, Australia

Department of Cardiothoracic Surgery, Western Australian Cardiothoracic Research and Audit Group, Fiona Stanley Hospital, Perth, WA, Australia.

出版信息

Interact Cardiovasc Thorac Surg. 2016 May;22(5):594-8. doi: 10.1093/icvts/ivw017. Epub 2016 Feb 23.

Abstract

OBJECTIVES

Deep sternal wound infection is a devastating complication of cardiac surgery. In the current era of increasing patient comorbidity, newer techniques must be evaluated in attempts to reduce the rates of deep sternal wound infection.

METHODS

A randomized controlled trial comparing sternal closure with traditional sternal wires in figure-8 formation with the Pioneer cabling system® from Medigroup after adult cardiac surgery was performed.

RESULTS

A total of 273 patients were enrolled with 137 and 135 patients randomized to sternal wires and cables group, respectively. Baseline characteristics between the two groups were well balanced. Deep sternal wound infection occurred in 0.7% of patients in the wires group and 3.7% of patients in the cables group (absolute risk difference = -3.0%, 95% confidence interval: -7.7 to 0.9%; P = 0.12). Patients in the cables group were extubated slightly earlier than those in the sternal wires group postoperatively (9.7 vs 12.8 h; P = 0.03). There was, however, no significant difference in hospital and follow-up pain scores or analgesia requirements.

CONCLUSIONS

The Pioneer sternal cabling system appears to facilitate early extubation after adult cardiac surgery, but it does not reduce the rate of deep sternal infectionAustralian New Zealand Clinical Trials Registry: ANZCTR-ACTRN12615000973516.

摘要

目的

深部胸骨伤口感染是心脏手术的一种毁灭性并发症。在患者合并症日益增多的当前时代,必须评估新的技术以试图降低深部胸骨伤口感染率。

方法

进行了一项随机对照试验,比较成人心脏手术后使用传统“8”字形胸骨钢丝进行胸骨闭合与使用美迪医疗集团的先锋线缆系统进行胸骨闭合的效果。

结果

共纳入273例患者,分别有137例和135例患者随机分配至胸骨钢丝组和线缆组。两组之间的基线特征平衡良好。钢丝组0.7%的患者发生深部胸骨伤口感染,线缆组为3.7%(绝对风险差异=-3.0%,95%置信区间:-7.7至0.9%;P=0.12)。线缆组患者术后拔管时间略早于胸骨钢丝组(9.7小时对12.8小时;P=0.03)。然而,在住院和随访疼痛评分或镇痛需求方面没有显著差异。

结论

先锋胸骨线缆系统似乎有助于成人心脏手术后早期拔管,但并未降低深部胸骨感染率。澳大利亚新西兰临床试验注册中心:ANZCTR-ACTRN12615000973516 。

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