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[关于发热伴血小板减少综合征流行病学特征的综述]

[A review on the epidemiologic features of severe fever with thrombocytopenia syndrome].

作者信息

Wang J Y, Wu H, Tong Z D, Yan J B, Li K F, Tang A

机构信息

School of Public Health, Nanchang University, Nanchang 330000, China; Department of Infectious Diseases Control and Prevention, Zhoushan Center for Disease Control and Prevention, Zhoushan 316021, China.

Department of Infectious Diseases Control and Prevention, Zhoushan Center for Disease Control and Prevention, Zhoushan 316021, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2016 Feb;37(2):294-8. doi: 10.3760/cma.j.issn.0254-6450.2016.02.029.

Abstract

Severe fever with Thrombocytopenia Syndrome (SFTS) is an emerging hemorrhagic fever disease in the rural areas of east-central China, which is caused by SFTSV-a newly discovered bunyavirus. SFTSV is most likely transmitted by tick bites but can also be transmitted within human beings. The onset of SFTS is sudden and with rapid progress, with main clinical manifestations as fever, thrombocytopenia, leucopenia and gastrointestinal and hepatorenal dysfunctions. Some patients may die from multiple organ failure, and the case fatality rate is approximately 10%. In this paper, we use the method of literature review to summarize the recent research progress of SFTS which includes the epidemic distribution characteristics, medium of transmission, host animals, transmission routes and susceptibility in the general population.

摘要

严重发热伴血小板减少综合征(SFTS)是一种在中国中东部农村地区新出现的出血热疾病,由一种新发现的布尼亚病毒——SFTS病毒引起。SFTS病毒很可能通过蜱虫叮咬传播,但也可在人与人之间传播。SFTS起病急骤且进展迅速,主要临床表现为发热、血小板减少、白细胞减少以及胃肠和肝肾功能障碍。部分患者可能死于多器官功能衰竭,病死率约为10%。在本文中,我们采用文献综述的方法总结SFTS的最新研究进展,内容包括流行分布特征、传播媒介、宿主动物、传播途径以及普通人群的易感性。

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