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巨大的幕上硬脑膜软骨瘤引发了一个问题:肿瘤在不表现出自身症状的情况下能长到多大?

Giant Dural Supratentorial Chondroma Generating the Question of How Large Can a Tumor Become Without Revealing Itself.

作者信息

Doukas Alexandros, Tallo Annamarie, Parvin Richard, Hans Volkmar, Daemi Pooya, Cheko Azad, Scholz Martin, Petridis Athanasios K

机构信息

Department of Neurosurgery, University Hospital , Kiel.

Department of Neurosurgery, Wedau Kliniken , Duisburg.

出版信息

Clin Pract. 2015 Dec 29;5(4):777. doi: 10.4081/cp.2015.777. eCollection 2015 Nov 5.

DOI:10.4081/cp.2015.777
PMID:26918096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4745590/
Abstract

Chondromas usually affect the small bones of hand and feet and account for only 0.5% of all intracranial tumors. We present a case of a giant, supratentorial meningeal chondroma in a 19-year old male patient and discuss the preoperative diagnostic findings as well as the appropriate treatment options. A 19-old male presented with headache, new onset of focal seizures and paresis of left upper extremity. Magnetic resonance imaging revealed a large right parietal tumor in the precentral region with local mass effect. The patient underwent right parietal craniotomy and gross total resection of the tumor. The histopathological report revealed a chondroma. Intradural supratentorial chondromas are extremely rare. As with other slow growing intracranial masses, they often reach a relatively large size before generating symptoms. Maximal surgical resection is the treatment of choice and if this is achieved no adjuvant therapy is necessary.

摘要

软骨瘤通常累及手足小骨,仅占所有颅内肿瘤的0.5%。我们报告一例19岁男性患者的巨大幕上脑膜软骨瘤病例,并讨论术前诊断结果及合适的治疗方案。一名19岁男性患者出现头痛、新发局灶性癫痫发作及左上肢无力。磁共振成像显示中央前区右侧顶叶有一个大肿瘤,伴有局部占位效应。患者接受了右侧顶叶开颅手术及肿瘤全切术。组织病理学报告显示为软骨瘤。硬脑膜内幕上软骨瘤极为罕见。与其他生长缓慢的颅内肿块一样,它们在产生症状之前往往会长得相对较大。手术全切是首选治疗方法,如果能够实现全切,则无需辅助治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/31d227f9cdba/cp-2015-4-777-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/f2fe67a77c19/cp-2015-4-777-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/4da1928c4df7/cp-2015-4-777-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/4ab92a0de346/cp-2015-4-777-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/31d227f9cdba/cp-2015-4-777-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/f2fe67a77c19/cp-2015-4-777-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/4da1928c4df7/cp-2015-4-777-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/4ab92a0de346/cp-2015-4-777-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beaf/4745590/31d227f9cdba/cp-2015-4-777-g004.jpg

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本文引用的文献

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Convexity dural chondroma: a case report with pathological and molecular analysis.凸面硬脑膜软骨瘤:一例伴有病理及分子分析的病例报告
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Intracranial cystic chondroma: a case report.颅内囊性软骨瘤:一例报告
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