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颅内软骨肉瘤:一例病例报告及文献综述

Intracranial chondrosarcoma: a case report and review of the literature.

作者信息

Chandler James P, Yashar Parham, Laskin William B, Russell Eric J

机构信息

Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

出版信息

J Neurooncol. 2004 May;68(1):33-9. doi: 10.1023/b:neon.0000024728.72998.7d.

Abstract

OBJECTIVE AND IMPORTANCE

Chondrosarcomas rarely occur intracranially away from the skull base. We present a case of a supratentorial dural-based, low-grade classic chondrosarcoma and emphasize salient imaging findings that assist in its diagnosis.

CLINICAL PRESENTATION

A 23-year-old female presented with new onset seizures. Multiple radiographic imaging studies identified a large left frontal mass with radiological findings that suggested the correct diagnosis.

INTERVENTION

The patient underwent a left frontal craniotomy and gross total resection of the lesion and associated dura.

CONCLUSION

Intracranial chondrosarcomas away from the skull based are extremely rare malignancies. As with other extra-axial masses, they often grow to a relatively large size before generating symptoms. Careful analysis of CT, MR, and angiographic imaging characteristics should suggest the correct diagnosis.

摘要

目的与重要性

软骨肉瘤极少发生于颅底以外的颅内区域。我们报告一例幕上硬脑膜起源的低级别经典型软骨肉瘤病例,并强调有助于其诊断的显著影像学表现。

临床表现

一名23岁女性因新发癫痫就诊。多项影像学检查发现左额叶有一巨大肿块,其影像学表现提示了正确诊断。

干预措施

患者接受了左额叶开颅手术,病变及相关硬脑膜被全切。

结论

颅底以外的颅内软骨肉瘤是极其罕见的恶性肿瘤。与其他轴外肿块一样,它们通常在产生症状前生长到相对较大的尺寸。仔细分析CT、MR和血管造影的影像学特征应能提示正确诊断。

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