Warner J G, Ullrich I H, Albrink M J, Yeater R A
Human Performance Laboratory, West Virginia University, Morgantown 26506.
Med Sci Sports Exerc. 1989 Oct;21(5):498-505.
Because both aerobic exercise and fish oil ingestion have been shown to decrease plasma lipids, we examined the effects of combining these modalities in hyperlipidemic subjects. Thirty-four subjects were randomly assigned to one of four groups as follows: fish oil and exercise (FE), N = 7, 50 ml of oil daily and 3 d.wk-1 of aerobic exercise; fish oil (F), N = 7, 50 ml of oil daily; corn oil (CN), N = 10, 50 ml of oil daily; and control (C), N = 10. Blood samples were drawn at baseline and at the end of 4, 8, and 12 wk. The FE and F groups showed significantly lower triglycerides with respect to treatment as compared to the CN and C groups. The FE, F, and CN groups exhibited lower total cholesterol values than the control group but were not different from each other. HDL cholesterol was significantly increased after treatment in the FE and F groups as compared to the CN and C groups. Serum apo-B, LDL cholesterol, and LDL protein decreased significantly in the FE group but not the F group from baseline to 12 wk. VO2max increased and percent fat decreased only in the FE group. In conclusion, aerobic exercise improved the effects of fish oil on LDL cholesterol and apo-B and improved fitness and body composition in hyperlipidemic subjects.
由于有氧运动和摄入鱼油均已被证明可降低血脂，我们研究了在高脂血症患者中联合使用这两种方式的效果。34名受试者被随机分为以下四组之一：鱼油与运动组（FE），N = 7，每日服用50毫升鱼油且每周进行3天有氧运动；鱼油组（F），N = 7，每日服用50毫升鱼油；玉米油组（CN），N = 10，每日服用50毫升玉米油；以及对照组（C），N = 10。在基线以及第4、8和12周结束时采集血样。与CN组和C组相比，FE组和F组在治疗后甘油三酯水平显著降低。FE组、F组和CN组的总胆固醇值均低于对照组，但彼此之间无差异。与CN组和C组相比，FE组和F组治疗后高密度脂蛋白胆固醇显著升高。从基线到第12周，FE组血清载脂蛋白B、低密度脂蛋白胆固醇和低密度脂蛋白蛋白显著降低，而F组未降低。仅FE组的最大摄氧量增加且体脂百分比降低。总之，有氧运动改善了鱼油对低密度脂蛋白胆固醇和载脂蛋白B的作用，并改善了高脂血症患者的健康状况和身体组成。
