Ozurdex（®）迁移至前房后的角膜毒性。
Corneal toxicity after Ozurdex(®) migration into anterior chamber.
作者信息
Bernal L, Estévez B
机构信息
Servicio de Oftalmología, Complejo Hospitalario Universitario Insular Materno Infantil, de Las Palmas de Gran Canaria, España.
Servicio de Oftalmología, Complejo Hospitalario Universitario Insular Materno Infantil, de Las Palmas de Gran Canaria, España.
出版信息
Arch Soc Esp Oftalmol. 2016 Jun;91(6):292-4. doi: 10.1016/j.oftal.2016.01.008. Epub 2016 Feb 24.
OBJECTIVE
To describe a case of corneal toxicity after migration of a dexamethasone implant into the anterior chamber.
CASE REPORT
A 62-year-old man with aphakia and a history of vitrectomy received a dexamethasone implant for a refractory Irvine-Gass syndrome. Thirty days later, the implant migrated into the anterior chamber causing endothelial contact with secondary corneal oedema that justified the removal of the implant without resolution of the oedema.
DISCUSSION
Clinical tolerability to dislocated implant is poor in cases with pre-existing corneal oedema, and because of this, it must be removed early. In cases of aphakia and vitrectomy, the increased risk of Ozurdex(®) dislocation justifies performing a prior endothelial count.
目的
描述一例地塞米松植入物移位至前房后发生角膜毒性的病例。
病例报告
一名62岁无晶状体且有玻璃体切割术病史的男性因难治性Irvine-Gass综合征接受了地塞米松植入物。30天后，植入物移位至前房，导致内皮接触并继发角膜水肿，这使得在水肿未消退的情况下取出了植入物。
讨论
在已有角膜水肿的病例中，移位植入物的临床耐受性较差，因此必须尽早取出。在无晶状体和玻璃体切割术的病例中，Ozurdex（®）移位风险增加，因此有必要事先进行内皮细胞计数。
Zotero 插件