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Efficient production of CYTL1 protein using mouse IgGκ signal peptide in the CHO cell expression system.

作者信息

Wang Xiaolin, Liu Huihui, Yuan Wanqiong, Cheng Yingying, Han Wenling

机构信息

Department of Immunology, Key Laboratory of Medical Immunology, Ministry of Health, School of Basic Medical Sciences, Peking University Center for Human Disease Genomics, Beijing 100191, China Peking University Center for Human Disease Genomics, Peking University Health Science Center, Beijing 100191, China.

Department of Immunology, Key Laboratory of Medical Immunology, Ministry of Health, School of Basic Medical Sciences, Peking University Center for Human Disease Genomics, Beijing 100191, China Peking University Center for Human Disease Genomics, Peking University Health Science Center, Beijing 100191, China

出版信息

Acta Biochim Biophys Sin (Shanghai). 2016 Apr;48(4):391-4. doi: 10.1093/abbs/gmw007. Epub 2016 Feb 27.

DOI:10.1093/abbs/gmw007
PMID:26922322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4886246/
Abstract
摘要

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本文引用的文献

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Generation and characterization of a novel human IgG1 antibody against vascular endothelial growth factor receptor 2.一种新型抗血管内皮生长因子受体2人IgG1抗体的产生与特性分析
Cancer Immunol Immunother. 2014 Sep;63(9):877-88. doi: 10.1007/s00262-014-1560-9. Epub 2014 Jun 4.
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Gene therapy of malignant solid tumors by targeting erbB2 receptors and by activating T cells.针对 erbB2 受体的基因治疗和 T 细胞激活治疗恶性实体瘤。
Cancer Biother Radiopharm. 2012 Dec;27(10):711-8. doi: 10.1089/cbr.2012.1246. Epub 2012 Sep 18.
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VSTM1-v2, a novel soluble glycoprotein, promotes the differentiation and activation of Th17 cells.VSTM1-v2，一种新型可溶性糖蛋白，促进 Th17 细胞的分化和激活。
Cell Immunol. 2012 Jul-Aug;278(1-2):136-42. doi: 10.1016/j.cellimm.2012.07.009. Epub 2012 Aug 16.
4
Cytokine-like 1 knock-out mice (Cytl1-/-) show normal cartilage and bone development but exhibit augmented osteoarthritic cartilage destruction.细胞因子样 1 敲除小鼠（Cytl1-/-）表现出正常的软骨和骨骼发育，但表现出增强的骨关节炎软骨破坏。
J Biol Chem. 2011 Aug 5;286(31):27206-13. doi: 10.1074/jbc.M111.218065. Epub 2011 Jun 7.
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Cell engineering and cultivation of chinese hamster ovary (CHO) cells.细胞工程与中国仓鼠卵巢（CHO）细胞的培养。
Curr Pharm Biotechnol. 2010 Apr;11(3):233-40. doi: 10.2174/138920110791111960.
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Cytokine-receptor pairing: accelerating discovery of cytokine function.
Nat Rev Drug Discov. 2004 Feb;3(2):160-70. doi: 10.1038/nrd1305.
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Gene design of signal sequence for effective secretion of protein.
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Molecular cloning and chromosomal mapping of a candidate cytokine gene selectively expressed in human CD34+ cells.在人CD34+细胞中选择性表达的一个候选细胞因子基因的分子克隆与染色体定位
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