Fahimzad Alireza, Eydian Zahra, Karimi Abdollah, Shiva Farideh, Sayyahfar Shirin, Kahbazi Manijeh, Rahbarimanesh Aliakbar, Sedighi Iraj, Arjmand Reza, Soleimani Gholamreza, Sanaei Dashti Anahita, Abdinia Babak, Mostafavi Nasser, Nikfar Roya, Abedini Masomeh, Rezaei Mohammad Sadegh, Mohammadpour Ali, Hashemian Houman, Hidari Hossein, Ghadiri Keyghobad, Entezari Heravi Reza
Pediatric Infectious Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Pediatrics, Zabol University of Medical Sciences, Zabol, Iran.
Arch Iran Med. 2016 Mar;19(3):204-9.
Antibiotics are among the most commonly prescribed drugs in pediatrics. Due to lack of uniformity in pediatric antimicrobial prescribing and the emergence of antibiotic resistance, appropriate drug utilization studies have been found to be crucial to evaluate whether these drugs are properly used.
Data were collected between January 2014 and February 2014 in 16 Iranian pediatric hospitals using a standardized method. The point prevalence survey included all inpatient beds.
Of 858 children, 571 (66.6%) received one or more antimicrobials. The indications were therapeutic in 60.6%. The parenteral route was used in 92.5% of therapeutic indications. Ceftriaxone was the most prescribed antimicrobials for therapeutic indications (32.4%) and combination-therapy was the most type of therapy in pediatric intelligent care unit (PICU).
According to results of this study, antibiotics' prescribing in pediatrics wards of Iranian hospitals is empirical. Therefore, for quality improvement of antimicrobial use in children continuous audit process and antibiotic prescriptions require further investigation.
抗生素是儿科最常用的处方药之一。由于儿科抗菌药物处方缺乏一致性以及抗生素耐药性的出现，适当的药物利用研究对于评估这些药物是否得到合理使用至关重要。
2014年1月至2014年2月期间，采用标准化方法在16家伊朗儿科医院收集数据。点患病率调查涵盖了所有住院床位。
在858名儿童中，571名（66.6%）接受了一种或多种抗菌药物治疗。其中60.6%的用药指征为治疗性。92.5%的治疗性用药采用了肠外给药途径。头孢曲松是治疗性用药中最常开具的抗菌药物（32.4%），联合治疗是儿科重症监护病房（PICU）中最常见的治疗方式。
根据本研究结果，伊朗医院儿科病房的抗生素处方是经验性的。因此，为提高儿童抗菌药物使用质量，持续审核流程和抗生素处方需要进一步研究。
