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[进食与食物偏好调节的分子机制]

[Molecular mechanism for feeding and food preference regulation].

作者信息

Minokoshi Yasuhiko

机构信息

Division of Endocrinology and Metabolism, Department of Developmental Physiology,National Institute for Physiological Sciences, Japan. Department of Physiological Sciences, SOKENDAI（The Graduate University for Advanced Studies School of Life Science）, Japan.

出版信息

Clin Calcium. 2016 Mar;26(3):405-11.

PMID:26923978
Abstract

Feeding behavior is regulated by homeostatic and hedonic mechanisms. NPY/AgRP neurons in the arcuate hypothalamus are involved in the homeostatic regulation, and dopaminergic neurons in the ventral tegmental area regulating the nucleus of accumbens are involved in the hedonic regulation, respectively. Food preference also appears to be regulated by both homeostatic and hedonic mechanisms. However, molecular mechanism for food preference regulation remains elusive and further studies are necessary.

摘要

进食行为受稳态和享乐机制调节。弓状下丘脑中的神经肽Y/刺鼠肽基因相关蛋白（NPY/AgRP）神经元参与稳态调节，而调节伏隔核的腹侧被盖区中的多巴胺能神经元分别参与享乐调节。食物偏好似乎也受稳态和享乐机制调节。然而，食物偏好调节的分子机制仍不清楚，需要进一步研究。

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