Ueno Takayoshi, Ozawa Hideto, Taira Masaki, Kanaya Tomomitsu, Toda Koichi, Kuratani Toru, Sawa Yoshiki
Department of Advanced Cardiovascular Therapeutics, Osaka University Graduate School of Medicine.
Circ J. 2016;80(4):1041-3. doi: 10.1253/circj.CJ-15-0973. Epub 2016 Feb 26.
Pulmonary valve replacement (PVR) is a common reoperation, typically required approximately 10 years following right ventricular outflow tract reconstruction and especially true in cases of tetralogy of Fallot. However, an improved prosthetic valve is required.
A fresh decellularized pulmonary allograft was used for PVR to correct pulmonary valve regurgitation in a 35-year-old man 33 years following tetralogy of Fallot repair. The postoperative course and short-term valve function were excellent. This is the first case of a decellularized pulmonary allograft in Japan.
Fresh decellularized pulmonary allografts have the potential to become a new source of material for PVR in patients who have undergone right ventricular outflow tract reconstruction.
肺动脉瓣置换术（PVR）是一种常见的再次手术，通常在右心室流出道重建后约10年需要进行，法洛四联症患者尤其如此。然而，需要一种改进的人工瓣膜。
一名35岁男性在法洛四联症修复术后33年，使用新鲜去细胞肺同种异体移植物进行PVR以纠正肺动脉瓣反流。术后病程及短期瓣膜功能良好。这是日本首例去细胞肺同种异体移植物病例。
新鲜去细胞肺同种异体移植物有可能成为右心室流出道重建患者PVR的新的材料来源。
