Müller H E
Staatliches Medizinaluntersuchungsamt, Braunschweig.
Zentralbl Bakteriol. 1989 Nov;272(1):30-5. doi: 10.1016/s0934-8840(89)80089-1.
A survey was undertaken on the occurrence of Protease in the human fecal flora and its coincidence with other well-documented enteropathogens such as Campylobacter, Salmonella, Shigella, Staphylococcus aureus, Yersinia, protozoa and rotavirus. A total of 2000 fecal specimens was investigated, 1000 from patients suffering from diarrhea and 1000 from healthy persons which served as controls. Proteus mirabilis was isolated more frequently from diarrhea cases than from healthy people. The difference was statistically significant (P less than 0.001). There was no correlation between its occurrence and isolation of Campylobacter, Salmonella, Shigella, Staphylococcus aureus, and protozoa. However, a questionable coincidence was found with rotavirus (P less than 0.2) and a more certain correlation with Yersinia enterocolitica (P less than 0.025). Proteus mirabilis in patients suffering from infection by other known enteropathogens was largely absent, suggesting that the organisms were independent causative agents of intestinal disorders. Notwithstanding this, they may additionally play a role as opportunists in enteric diseases due to some other pathogens.
对人类粪便菌群中蛋白酶的存在情况及其与其他有充分文献记载的肠道病原体（如弯曲杆菌、沙门氏菌、志贺氏菌、金黄色葡萄球菌、耶尔森氏菌、原生动物和轮状病毒）的共存情况进行了一项调查。共调查了2000份粪便标本，其中1000份来自腹泻患者，1000份来自健康人作为对照。奇异变形杆菌在腹泻病例中的分离频率高于健康人。差异具有统计学意义（P小于0.001）。其出现与弯曲杆菌、沙门氏菌、志贺氏菌、金黄色葡萄球菌和原生动物的分离之间没有相关性。然而，发现与轮状病毒有可疑的共存关系（P小于0.2），与小肠结肠炎耶尔森氏菌有更确定的相关性（P小于0.025）。感染其他已知肠道病原体的患者中基本不存在奇异变形杆菌，这表明这些微生物是肠道疾病的独立病原体。尽管如此，它们可能在由其他一些病原体引起的肠道疾病中作为机会致病菌发挥额外作用。
