Research Center on Public Health, University of Milan-Bicocca, Monza, Italy.
Section of Digestive Diseases, International Center for Digestive Health, Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Hepatology. 2016 Oct;64(4):1331-42. doi: 10.1002/hep.28527. Epub 2016 Apr 4.
In the current context of rising health care costs and decreasing sustainability, it is becoming increasingly common to resort to decision analytical modeling and health economics evaluations. Decision analytic models are analytical tools that help decision makers to select the best choice between alternative health care interventions, taking into consideration the complexity of the disease, the socioeconomic context, and the relevant differences in outcomes. We present a brief overview of the use of decision analytical models in health economic evaluations and their applications in the area of liver diseases. The aim is to provide the reader with the basic elements to evaluate health economic analysis reports and to discuss some limitations of the current approaches, as highlighted by the case of the therapy of chronic hepatitis C. To serve its purpose, health economics evaluations must be able to do justice to medical innovation and the market while protecting patients and society and promoting fair access to treatment and its economic sustainability.
New approaches and methods able to include variables such as prevalence of the disease, budget impact, and sustainability into the cost-effectiveness analysis are needed to reach this goal. (Hepatology 2016;64:1331-1342).
在医疗成本不断上升和可持续性不断下降的当前背景下，越来越多地采用决策分析模型和健康经济学评价。决策分析模型是一种分析工具，可帮助决策者在考虑疾病的复杂性、社会经济背景以及相关结果差异的情况下，在各种医疗保健干预措施之间进行选择。
我们简要概述了决策分析模型在健康经济学评价中的应用及其在肝脏疾病领域的应用。目的是为读者提供评估健康经济学分析报告的基本要素，并讨论当前方法的一些局限性，例如慢性丙型肝炎治疗的案例。
需要新的方法和模型，以便将疾病的流行程度、预算影响和可持续性等变量纳入成本效益分析中，以实现这一目标。
