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吉西他滨诱导的亚急性皮肤型红斑狼疮:一例报告

Gemcitabine-Induced Subacute Cutaneous Lupus Erythematosus: A Case Report.

作者信息

Ben Zvi Masha, Vaknine Hananya, Menczer Joseph, Peled Ofri, Ben Shem Erez, Schreiber Letizia, Levy Tally

出版信息

Chemotherapy. 2016;61(5):236-9. doi: 10.1159/000443762. Epub 2016 Mar 1.

Abstract

Subacute cutaneous lupus erythematosus (SCLE) is a rare eruption related to several pharmacological and chemotherapy agents. We present a 63-year-old female with recurrent epithelial ovarian cancer who developed SCLE after administration of gemcitabine. Following discontinuation of gemcitabine and after oral steroid treatment, all skin lesions disappeared. In view of the extensive use of gemcitabine in recurrent ovarian cancer, it is important to be aware of the possibility of SCLE occurrence in these patients.

摘要

亚急性皮肤型红斑狼疮(SCLE)是一种与多种药物及化疗药物相关的罕见皮疹。我们报告一名63岁复发性上皮性卵巢癌女性患者,在使用吉西他滨后发生了SCLE。停用吉西他滨并经口服类固醇治疗后,所有皮肤病变均消失。鉴于吉西他滨在复发性卵巢癌中的广泛应用,认识到这些患者发生SCLE的可能性很重要。

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