Mottet Nicolas, Saada Julien, Jani Jacques, Martin Alain, Riethmuller Didier, Zerah Michel, Benachi Alexandra
Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Antoine Béclère, AP-HP, Université Paris Sud, Paris, France.
Fetal Diagn Ther. 2016;40(3):224-230. doi: 10.1159/000443731. Epub 2016 Mar 2.
Sonographic evaluation of the fetal conus medullaris (CM) level is not reproducible. The objectives of this study were to determine the normal position of the fetal CM during pregnancy as well as the normal intradural filum terminale (FT) length and to evaluate their use in detecting tethered cord.
This is a prospective evaluation of normal singleton pregnancies examined by sonography from 17 weeks of gestation to term. Each sonographer had to identify the top of the first sacral vertebra (S1) to measure the distance between it and the conus extremity (CM-S1 distance). The intradural FT distance was measured with 5- to 8-MHz probes.
194 consecutive pregnant women were included. The CM and intradural FT were demonstrated clearly in 164 (84%) cases. The mean CM-S1 distance was 20.6 mm (range 0.5-42). The mean intradural FT distance was 27.9 mm (range 6.6-49.3). Linear regression analysis showed a significant association between both those distances and gestational age (p < 0.05). In cases of tethered cord, the mean CM-S1 distance and the mean intradural FT distance were both below the 5th percentile.
Prenatal evaluation of the CM and the intradural FT is feasible and reproducible and seems useful in detecting tethered cord.
超声评估胎儿圆锥水平的结果不可重复。本研究的目的是确定孕期胎儿圆锥的正常位置以及硬脊膜内终丝的正常长度,并评估它们在检测脊髓栓系中的应用。
这是一项对单胎妊娠进行前瞻性评估的研究,从妊娠17周超声检查至足月。每位超声检查人员必须识别第一骶椎(S1)的顶部,测量其与圆锥末端之间的距离(圆锥 - S1距离)。使用5至8兆赫兹探头测量硬脊膜内终丝的距离。
纳入194例连续孕妇。164例(84%)病例中圆锥和硬脊膜内终丝显示清晰。圆锥 - S1距离的平均值为20.6毫米(范围0.5 - 42)。硬脊膜内终丝距离的平均值为27.9毫米(范围6.6 - 49.3)。线性回归分析显示这两个距离与孕周之间均存在显著相关性(p < 0.05)。在脊髓栓系病例中,圆锥 - S1距离平均值和硬脊膜内终丝距离平均值均低于第5百分位数。
产前评估圆锥和硬脊膜内终丝是可行且可重复的,似乎对检测脊髓栓系有用。