Current Trends in the Incidence and Presentation of Oropharyngeal Cancer.

The prevalence and behavior of oropharyngeal cancers have dramatically changed over the past 30 years. It is now clear that human papillomavirus (HPV) plays a major role in the incidence of head and neck cancers in the general population and among patients with HIV infection. This article reviews the current knowledge about oropharyngeal cancers for their epidemiology, pathogenesis, clinical behavior, treatment and prevention. This review further examines the subset of oropharyngeal cancers among the HIV-seropositive patients.