Yu Huanxin, Li Haiyan, Liu Gang
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(21):1847-9.
To Summarize and analyze the clinical characteristics and treatment of patients with spontaneous cerebrospinal fluid rhinorrhea, and to explore the related factors of recurrence.
Retrospective- ly analyze the clinical data of 58 patients of spontaneous cerebrospinal fluid rhinorrhea from July 2002 to July 2012, combined with its clinical characteristics, and statistically analyze the related recurrence factors.
Fifty-eight cases were accepted the nasal endoscopic repairment of cerebrospinal fluid rhinorrheak, follow-up 3 years, 20 cases (34.5%) recurred, 1 case recurred in half a year after operation. In the first year, there were 10 cases recurred. In the second year there were 9 cases recurred, and 1 case recurred in the third year. Through multiariable analysis it was found that higher BMI, empty sella and skull base bone defect were the independent risk factors influencing the recurrence of spontaneous cerebrospinal fluid rhinorrhea (P < 0.05).
The recurrence rate of spontaneous cerebrospinal fluid rhinorrhea is high, needing long-term follow-up. Higher BMI, empty sella, skull base bone defect are independent risk factors of recurrence of the disease, and the treatment should be individualized.
总结分析自发性脑脊液鼻漏患者的临床特点及治疗情况，探讨复发的相关因素。
回顾性分析2002年7月至2012年7月收治的58例自发性脑脊液鼻漏患者的临床资料，结合其临床特点，对相关复发因素进行统计学分析。
58例患者均接受了鼻内镜下脑脊液鼻漏修补术，随访3年，20例（34.5%）复发，1例术后半年复发。第1年复发10例，第2年复发9例，第3年复发1例。多因素分析发现，较高的体重指数、空蝶鞍及颅底骨质缺损是影响自发性脑脊液鼻漏复发的独立危险因素（P<0.05）。
自发性脑脊液鼻漏复发率较高，需长期随访。较高的体重指数、空蝶鞍、颅底骨质缺损是该病复发的独立危险因素，治疗应个体化。
