Prencipe M, Marini C
Department of Neurology, University of L'Aquila, Italy.
Eur Neurol. 1989;29 Suppl 2:27-9. doi: 10.1159/000116462.
Leuko-araiosis (LA) is a descriptive term coined by Hachinsky et al. to indicate bilateral and nearly symmetrical areas of decreased density of the periventricular white matter and centra semiovalia seen on CT or MRI scan. These findings are frequently observed in elderly people, but they seem to be more frequent or more severe in demented patients regardless of the etiology. Neurological abnormalities observed in patients with LA are nonspecific and insufficient to describe a definite clinical picture. The hypothesis that LA could be vascular in origin, even in Alzheimer patients is attractive but unproven.
脑白质疏松症（LA）是哈钦斯基等人创造的一个描述性术语，用于指在CT或MRI扫描上看到的脑室周围白质和半卵圆中心密度降低的双侧且几乎对称的区域。这些发现常在老年人中观察到，但无论病因如何，在痴呆患者中似乎更常见或更严重。LA患者中观察到的神经学异常是非特异性的，不足以描述明确的临床症状。即使在阿尔茨海默病患者中，LA可能起源于血管的假说很有吸引力，但尚未得到证实。
