Haustein U F, Seebacher C, Taube K M
Dermatol Monatsschr. 1989;175(12):751-6.
73 patients with fungal infections due to dermatophytes (49), yeasts (16) and Malassezia furfur (8) could be cured clinically in 71% and mycologically in 88% of cases by the application of Mycontral-Lotion or -cream twice daily for 33 days on average. In 28% improvement could be reached, in one patient the therapy failed. Treatment is simple, clean and well acceptable. Side-effects occurred as slight redness, transient burning and pruritus on the eroded skin in the initial phase in 8 patients (11%). Mykontral contains 1% tioconazole as a modern imidazol compound. It has been characterized as an effective topical broad spectrum antimycotic agent. Its introduction and application in the GDR is to be recommended.
73例由皮肤癣菌(49例)、酵母菌(16例)和糠秕马拉色菌(8例)引起真菌感染的患者,平均每天外用Mycontral洗液或乳膏两次,持续33天,临床治愈率达71%,真菌学治愈率达88%。28%的患者病情有所改善,1例患者治疗失败。该治疗方法简单、清洁且易于接受。8例患者(11%)在初始阶段出现轻微发红、短暂烧灼感和糜烂皮肤瘙痒等副作用。Mykontral含有1%的噻康唑,这是一种新型咪唑类化合物。它被认为是一种有效的外用广谱抗真菌剂。推荐在民主德国引入和应用该药物。