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大动脉转位时冠状动脉模式的超声心动图与手术相关性

Echocardiographic and Surgical Correlation of Coronary Artery Patterns in Transposition of the Great Arteries.

作者信息

Fundora Michael P, Aregullin Enrique Oliver, Wernovsky Gil, Welch Elizabeth M, Muniz Juan-Carlos, Sasaki Nao, Hannan Robert L, Burke Redmond P, Lopez Leo

机构信息

Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.

Department of Cardiovascular Surgery, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.

出版信息

Congenit Heart Dis. 2016 Dec;11(6):570-577. doi: 10.1111/chd.12338. Epub 2016 Mar 2.

Abstract

OBJECTIVE

Determine the accuracy of echocardiography to diagnose coronary anatomy in transposition of the great arteries and to evaluate the effect of accuracy on surgical outcomes and changes in accuracy over time.

DESIGN

Retrospective chart review of neonates admitted February 1999 to March 2013 with transposition. Coronary pattern from the preoperative echocardiogram and operative reports were collected and compared with determine diagnostic accuracy. Coronary patterns were further confirmed by intraoperative images taken during surgery.

SETTING

Tertiary care children's hospital.

PATIENTS

Neonates with transposition of the great arteries and planned arterial switch operation with an echo and operative report or image describing the coronaries.

INTERVENTIONS

Not applicable.

OUTCOME MEASURES

Accuracy of echocardiography to diagnose coronary anatomy in transposition, and to identify factors related to correct diagnosis.

RESULTS

One hundred forty-two patients met inclusion criteria with 122 correctly diagnosed, 16 incorrect, and 4 inconclusive. Accuracy was 86%, with 95% accuracy in patients with typical coronary patterns, 85% with the most common variant (left coronary from the leftward sinus and right and circumflex from the rightward sinus), and 61% with less common patterns. Typical and common variants were more likely to be correct than atypical patterns (P < .001). Cases with ventricular septal defect were more likely to have correctly diagnosed coronaries than with an intact ventricular septum (94% vs. 79%, P = .01). There was no change in accuracy over time (P > .05). There was no difference in duration of cardiopulmonary bypass, cross-clamp times, length of stay, or postoperative stay between the correct and incorrectly diagnosed groups (P > .05).

CONCLUSIONS

In our center, accuracy of echocardiographic imaging of the coronary arteries in transposition was 86% without improvement over time, and perioperative outcomes were not affected by diagnostic accuracy. Further invasive imaging may not be necessary to determine the coronary pattern in this lesion.

摘要

目的

确定超声心动图诊断大动脉转位时冠状动脉解剖结构的准确性,并评估准确性对手术结果的影响以及随时间推移准确性的变化。

设计

对1999年2月至2013年3月收治的大动脉转位新生儿进行回顾性病历审查。收集术前超声心动图和手术报告中的冠状动脉模式,并进行比较以确定诊断准确性。冠状动脉模式通过手术期间拍摄的术中图像进一步确认。

地点

三级儿童专科医院。

患者

患有大动脉转位且计划进行动脉调转手术的新生儿,并有超声心动图及描述冠状动脉的手术报告或图像。

干预措施

不适用。

观察指标

超声心动图诊断大动脉转位时冠状动脉解剖结构的准确性,以及确定与正确诊断相关的因素。

结果

142例患者符合纳入标准,其中122例诊断正确,16例错误,4例不确定。准确性为86%,典型冠状动脉模式患者的准确性为95%,最常见变异型(左冠状动脉发自左窦,右冠状动脉和回旋支发自右窦)患者的准确性为85%,少见模式患者的准确性为61%。典型和常见变异型比非典型模式更有可能诊断正确(P < 0.001)。有室间隔缺损的病例比室间隔完整的病例更有可能正确诊断冠状动脉(94%对79%,P = 0.01)。随着时间推移,准确性没有变化(P > 0.05)。正确诊断组和错误诊断组之间在体外循环时间、主动脉阻断时间、住院时间或术后住院时间方面没有差异(P > 0.05)。

结论

在我们中心,大动脉转位时冠状动脉超声心动图成像的准确性为86%,且随着时间推移没有提高,围手术期结果不受诊断准确性的影响。对于确定该病变的冠状动脉模式,可能无需进一步的有创成像检查。

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