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大动脉转位患者中一种罕见的大动脉空间关系:后位主动脉及其对预后的影响。

A rare spatial relation of the great arteries in patients with transposition of the great arteries: Posterior aorta and its effect on outcomes.

作者信息

Ayyıldız Pelin, Sevinç Şengül Fatma, Duras Ensar, Öztürk Erkut, Haydin Sertaç, Güzeltaş Alper

机构信息

Department of Pediatric Cardiology, University of Health Sciences, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye.

Department of Pediatric Cardiology, İstanbul University of Health Sciences, Başakşehir Cam and Sakura Hospital, İstanbul, Türkiye.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2024 Oct 30;32(4):394-401. doi: 10.5606/tgkdc.dergisi.2024.26097. eCollection 2024 Oct.

Abstract

BACKGROUND

This study aimed to evaluate patients diagnosed with posterior transposition of the great arteries (TGA) in detail.

METHODS

This retrospective study included 192 patients (155 males, 37 females; mean age: 0.4±0.9 month; range, 0.1 to 6 month) with TGA who were followed between August 1, 2016, and August 1, 2022. Patients with ventriculoarterial discordance, normal vessel relationship, and mitral-aortic continuity were considered posterior TGA. Demographic features, clinical findings, echocardiographic data, and surgical results of each patient were recorded.

RESULTS

Posterior TGA was present in 11 (5.7%) of the patients. The median age of patients with posterior TGA at the time of surgery was two months (interquartile range [IQR], 1-3 months), and their median body weight was 6.2 kg (IQR, 5-7.2 kg). The median oxygen saturation of the patients was 85% (IQR, 80-90%). A ventricular septal defect was present in all patients on echocardiography. There was also nonrestrictive atrial septal defect and patent ductus arteriosus in four patients, and one patient had arcus aorta hypoplasia. A coronary anomaly was determined in eight of the patients during surgery. These were 1LRCA2Cx in three cases, 1LRCx in three cases, 1R2LCx in one case, and 1L2RCx in one case. Arterial switch operation and ventricular septal defect closure was performed in 10 patients initially and in one patient after a pulmonary banding operation. The median cardiopulmonary bypass time was 190 min (IQR, 170-210 min). The Lecompte maneuver was not performed in any of the patients. The median stay in the intensive care unit and the hospital was 7 days (IQR, 5-10 days) and 16 days (IQR, 14-18 days), respectively. Two patients died in the early postoperative period.

CONCLUSION

In patients with suspected congenital heart disease, a segmental echocardiographic evaluation should be performed, and it should be kept in mind that the aorta may be located posteriorly as a rare spatial relationship in patients with TGA.

摘要

背景

本研究旨在详细评估被诊断为大动脉转位(TGA)的患者。

方法

这项回顾性研究纳入了2016年8月1日至2022年8月1日期间接受随访的192例TGA患者(男155例,女37例;平均年龄:0.4±0.9个月;范围为0.1至6个月)。心室动脉不一致、血管关系正常且二尖瓣 - 主动脉连续的患者被视为后位TGA。记录每位患者的人口统计学特征、临床发现、超声心动图数据及手术结果。

结果

11例(5.7%)患者存在后位TGA。后位TGA患者手术时的中位年龄为2个月(四分位间距[IQR],1 - 3个月),中位体重为6.2千克(IQR,5 - 7.2千克)。患者的中位血氧饱和度为85%(IQR,80 - 90%)。超声心动图显示所有患者均存在室间隔缺损。4例患者还存在非限制性房间隔缺损和动脉导管未闭,1例患者存在主动脉弓发育不全。手术过程中8例患者发现冠状动脉异常。其中3例为1LRCA2Cx,3例为1LRCx,1例为1R2LCx,1例为1L2RCx。最初10例患者及1例在进行肺动脉环扎术后的患者接受了动脉调转术和室间隔缺损修补术。中位体外循环时间为190分钟(IQR,170 - 210分钟)。所有患者均未行Lecompte maneuver。在重症监护病房和医院的中位住院时间分别为7天(IQR,5 - 10天)和16天(IQR,14 - 18天)。2例患者在术后早期死亡。

结论

对于疑似先天性心脏病患者,应进行分段超声心动图评估,并且应牢记在TGA患者中,主动脉可能以后位这种罕见的空间关系存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/386f/11620528/d369d13edea4/TJTCS-2024-32-4-394-401-F1.jpg

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