Das G
Division of Cardiology, UND School of Medicine, Fargo 58102.
Int J Clin Pharmacol Ther Toxicol. 1989 Dec;27(12):569-77.
Observations of significantly lower total cholesterol, low density lipoprotein (LDL) cholesterol and higher levels of high density lipoprotein (HDL) cholesterol among Eskimos as compared to Danes in all age groups and both genders, and the current emphasis on the role of cholesterol in atherosclerosis have stimulated several studies that have examined the effects of dietary fish or fish oil supplements on plasma lipids. Conclusions from these studies suggest a favorable change in the plasma lipids in subjects with higher intake of dietary fish or those receiving fish oil supplements towards a decreased incidence of atherosclerosis and hence the coronary artery disease. This article is an attempt to review the current understanding of the effects of fish oil on blood lipids and its role in the heart disease.
与丹麦人相比,各年龄组和男女两性的爱斯基摩人总胆固醇、低密度脂蛋白(LDL)胆固醇显著更低,高密度脂蛋白(HDL)胆固醇水平更高。目前对胆固醇在动脉粥样硬化中作用的重视促使了多项研究,这些研究探讨了食用鱼类或鱼油补充剂对血脂的影响。这些研究得出的结论表明,饮食中鱼类摄入量较高或服用鱼油补充剂的受试者血脂有有利变化,可降低动脉粥样硬化及冠心病的发病率。本文旨在综述目前对鱼油对血脂影响及其在心脏病中作用的认识。