Breyan D, Schilder H
Oral Surg Oral Med Oral Pathol. 1977 Sep;44(3):437-55. doi: 10.1016/0030-4220(77)90415-7.
Collagen secretion and maturation were investigated at the ultrastructural level. Pulp tissue from the continuously growing incisor of the rat provided excellent material for studying the secretory aspects of the tropocollagen. More mature human pulp material proved valuable in viewing the collagen fibril. A networklike arrangement of fibroblasts and fibrocytes was noted. Various types of cell junction were found in all specimens. The finding of a nexus junction was particularly interesting. It is hypothesized that connected cell systems rather than single cells might be the functional units involved in collagen formation.
在超微结构水平上研究了胶原蛋白的分泌和成熟过程。大鼠不断生长的切牙的牙髓组织为研究原胶原蛋白的分泌方面提供了极佳的材料。更成熟的人类牙髓材料在观察胶原纤维方面被证明具有价值。观察到成纤维细胞和纤维细胞呈网络状排列。在所有标本中均发现了各种类型的细胞连接。发现缝隙连接尤其有趣。据推测，参与胶原蛋白形成的功能单位可能是相连的细胞系统而非单个细胞。
