Papadatou-Pastou Marietta, Martin Maryanne, Mohr Christine
a Research Centre for Psychophysiology and Education , National and Kapodistrian University of Athens , Athens , Greece.
b Department of Experimental Psychology , University of Oxford , Oxford , UK.
Laterality. 2017 Mar;22(2):123-156. doi: 10.1080/1357650X.2016.1149485. Epub 2016 Mar 2.
Behavioural and cerebral lateralization are thought to be controlled, at least in part, by prenatal testosterone (T) levels, explaining why sex differences are found in both laterality traits. The present study investigated hormonal effects on laterality using adult salivary T levels, to explore the adequacy of competing theories: the Geschwind, Behan and Galaburda, the callosal, and the sexual differentiation hypotheses. Sixty participants (15 right-handers and 15 left-handers of each sex) participated. Behavioural lateralization was studied by means of hand preference tests (i.e., the Edinburgh Handedness Inventory and the Quantification of Hand Preference test) and a hand skill test (i.e., the Peg-Moving test) whereas cerebral lateralization for language was studied using the Consonant-Vowel Dichotic Listening test and the Visual Half-Field Lexical Decision test. Salivary T and cortisol (C) concentrations were measured by luminescence immunoassay. Canonical correlations did not reveal significant relationships between T levels and measures of hand preference, hand skill, or language laterality. Thus, our findings add to the growing literature showing no relationship between T concentrations with behavioural or cerebral lateralization. It is claimed that prenatal T is not a major determinant of individual variability in either behavioural or cerebral lateralization.
行为和大脑的偏侧化被认为至少部分受产前睾酮（T）水平的控制，这就解释了为什么在偏侧性特征方面会存在性别差异。本研究使用成人唾液中的T水平来探究激素对偏侧化的影响，以探讨几种相互竞争的理论的合理性：即盖施温德、贝汉和加拉布尔达理论、胼胝体理论以及性分化假说。60名参与者（每种性别中有15名右利手和15名左利手）参与了研究。通过手偏好测试（即爱丁堡利手量表和手偏好量化测试）和一项手部技能测试（即移 peg 测试）来研究行为偏侧化，而使用辅音 - 元音双耳分听测试和视觉半视野词汇判定测试来研究语言的大脑偏侧化。通过发光免疫测定法测量唾液中的T和皮质醇（C）浓度。典型相关分析未揭示T水平与手偏好、手部技能或语言偏侧化测量之间的显著关系。因此，我们的研究结果进一步丰富了越来越多的文献，这些文献表明T浓度与行为或大脑偏侧化之间没有关系。据称，产前T不是行为或大脑偏侧化个体差异的主要决定因素。
