核仁组成区嗜银蛋白（AgNORs）在鉴别滤泡性增生和滤泡性淋巴瘤方面是否有用？
Are AgNORs useful in distinguishing follicular hyperplasia from follicular lymphoma?
作者信息
Cronin K, Loftus B M, Dervan P A
机构信息
Department of Pathology, Mater Misericordiae Hospital, Dublin, Eire.
出版信息
J Clin Pathol. 1989 Dec;42(12):1267-8. doi: 10.1136/jcp.42.12.1267.
Abstract
Argyrophilic nucleolar organiser regions (AgNORs) in 28 follicular lymphomas and 30 lymph nodes showing reactive follicular hyperplasia were studied to see if they were helpful in distinguishing follicular lymphoma from follicular hyperplasia in paraffin wax tissue sections. Mean nuclear counts were greater in follicular hyperplasia (3.71 v 3.11). This difference was significant but counts overlapped so much that they were of no practical value in distinguishing between both conditions. Higher counts may reflect greater proliferative activity in follicular hyperplasia.
摘要
对28例滤泡性淋巴瘤和30例表现为反应性滤泡增生的淋巴结中的嗜银核仁组成区（AgNORs）进行了研究，以观察其在石蜡组织切片中区分滤泡性淋巴瘤与滤泡增生是否有帮助。滤泡增生中的平均核计数更高（3.71对3.11）。这种差异具有统计学意义，但计数重叠太多，以至于在区分这两种情况时没有实际价值。较高的计数可能反映了滤泡增生中更强的增殖活性。
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