Kerty E, Russell D, Bakke S J, Nyberg-Hansen R, Rootwell K
Department of Neurology, National Hospital, University of Oslo, Norway.
J Neurol Neurosurg Psychiatry. 1989 Dec;52(12):1345-50. doi: 10.1136/jnnp.52.12.1345.
Regional cerebral blood flow (rCBF) and cerebral vasoreactivity were assessed in 28 consecutive patients who presented with retinal ischaemic symptoms, without clinical or cerebral CT evidence of cerebral ischaemia. rCBF was measured using xenon-133 inhalation and single photon emission computed tomography before and 20 minutes after the intravenous administration of 1 g acetazolamide. The findings suggest that patients with retinal ischaemic symptoms alone due to carotid atherosclerosis often have a carotid lesion which is of haemodynamic significance with regard to cerebral perfusion and vasoreactivity. Furthermore, localized areas with reduced cerebral perfusion may also be present in some patients, without evidence of precerebral carotid occlusive disease.
对28例出现视网膜缺血症状但无脑缺血临床或脑CT证据的连续患者进行了局部脑血流量（rCBF）和脑血管反应性评估。在静脉注射1g乙酰唑胺前及注射后20分钟，采用氙-133吸入和单光子发射计算机断层扫描测量rCBF。研究结果表明，仅因颈动脉粥样硬化出现视网膜缺血症状的患者，其颈动脉病变在脑灌注和血管反应性方面往往具有血流动力学意义。此外，部分患者可能存在脑灌注降低的局部区域，但无前脑颈动脉闭塞性疾病的证据。
