对奇瓦·L·M和冈萨雷斯 - 马丁·A所著题为《热灌注化疗（HIPEC）治疗晚期复发性卵巢癌的批判性评估》的综述的评论
Commment on the review entitled "A critical appraisal of hyperthermic intraperitoneal chemotherapy (HIPEC) in the treatment of advanced and recurrent ovarian cancer" by Chiva LM and Gonzalez-Martin A.
作者信息
Deraco Marcello, Kusamura Shigeki, Baratti Dario
机构信息
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Department of surgery, Colorectal Cancer Unit, Peritoneal Surface Malignancies Program, Via Venezian, 1, Milano, MI Cap 20133, Italy.
出版信息
Gynecol Oncol Rep. 2015 Nov 28;15:7-8. doi: 10.1016/j.gore.2015.11.002. eCollection 2016 Jan.
Abstract
•We raised some methodological concerns and made some comments on the systematic review by Chiva and colleague.•To state that Cytoreduction & HIPEC is not beneficial in front line and platinum sensitive recurrence is highly disputable.•Anyway, the combined treatment should be offered in the context of clinical trial; randomized data are urgently needed.
摘要
•我们提出了一些方法学方面的问题，并对奇瓦及其同事的系统评价发表了一些评论。
•声称细胞减灭术及热灌注化疗对一线铂敏感复发患者无益处，这极具争议性。
•无论如何，联合治疗应在临床试验的背景下进行；迫切需要随机对照数据。
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本文引用的文献
1
A critical appraisal of hyperthermic intraperitoneal chemotherapy (HIPEC) in the treatment of advanced and recurrent ovarian cancer.腹腔内热灌注化疗（HIPEC）治疗晚期和复发性卵巢癌的评价。
Gynecol Oncol. 2015 Jan;136(1):130-5. doi: 10.1016/j.ygyno.2014.11.072. Epub 2014 Nov 28.
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Survival impact of complete cytoreduction to no gross residual disease for advanced-stage ovarian cancer: a meta-analysis.晚期卵巢癌完全肿瘤细胞减灭术至无肉眼残留病灶对生存的影响：一项荟萃分析。
Gynecol Oncol. 2013 Sep;130(3):493-8. doi: 10.1016/j.ygyno.2013.05.040. Epub 2013 Jun 6.
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Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy as upfront therapy for advanced epithelial ovarian cancer: multi-institutional phase-II trial.细胞减灭术和腹腔热灌注化疗作为晚期上皮性卵巢癌的初始治疗：多机构 II 期试验。
Gynecol Oncol. 2011 Aug;122(2):215-20. doi: 10.1016/j.ygyno.2011.05.004. Epub 2011 Jun 12.
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Neoadjuvant chemotherapy or primary surgery in advanced ovarian cancer.晚期卵巢癌的新辅助化疗或初次手术
N Engl J Med. 2010 Dec 9;363(24):2370-1; author reply 2372. doi: 10.1056/NEJMc1011061.
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Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer.新辅助化疗与初始肿瘤细胞减灭术用于 IIIC 或 IV 期卵巢癌。
N Engl J Med. 2010 Sep 2;363(10):943-53. doi: 10.1056/NEJMoa0908806.
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Safety and potential benefit of hyperthermic intraperitoneal chemotherapy (HIPEC) in peritoneal carcinomatosis from primary or recurrent ovarian cancer.原发性或复发性卵巢癌腹膜转移患者行腹腔内热灌注化疗（HIPEC）的安全性和潜在获益。
J Surg Oncol. 2010 Nov 1;102(6):663-70. doi: 10.1002/jso.21682.
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Improved progression-free and overall survival in advanced ovarian cancer as a result of a change in surgical paradigm.手术模式的改变使晚期卵巢癌的无进展生存期和总生存期得到改善。
Gynecol Oncol. 2009 Jul;114(1):26-31. doi: 10.1016/j.ygyno.2009.03.018. Epub 2009 Apr 23.
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Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a Phase III Trial of the Gynecologic Cancer Intergroup.晚期卵巢癌新型铂类治疗方案的评估：妇科肿瘤协作组的一项III期试验
J Clin Oncol. 2009 Mar 20;27(9):1419-25. doi: 10.1200/JCO.2008.19.1684. Epub 2009 Feb 17.
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