Su Hsuan, Pandey Deeksha, Liu Ling-Yu, Yen Chih-Feng, Wang Chin-Jung, Huang Kuan-Gen, Lee Chyi-Long
*Division of Gynecologic Endoscopy, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou Chang Gung University School of Medicine, Tao-Yuan, Taiwan; †Department of Obstetrics and Gynecology, KMC Manipal, Manipal University, Karnataka, India; ‡Graduate Institute of Clinical Medical Sciences, Chang Gung University School of Medicine, Tao-Yuan, Taiwan; and §Department of Obstetrics and Gynecology, Chang GungMemorial Hospital at Keelung & Lovers Lake Branch, Keelung City, Taiwan.
Int J Gynecol Cancer. 2016 May;26(4):705-10. doi: 10.1097/IGC.0000000000000676.
This study aimed to evaluate a specific glomerular pattern for prognostication of endometrial cancer (EC).
The office hysteroscopy's picture and video of 4197 women were reviewed, 48 women who were suspected of type I EC were analyzed: 26 have glomerular pattern (group 1) and 22 without it (group 2).
The histopathological grading after hysterectomy with glomerular pattern had grade 2 or grade 3 disease on final histology (n = 25; 96%). The sensitivity and specificity of this test were 84.6% and 81.8%, respectively, with a likelihood ratio of 4:6 in predicting and prognosticating those women who have high-grade tumor or invasive disease.
This hysteroscopic picture might be used as a novel marker for risk stratification of EC.
