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产科患者硬膜穿刺后头痛预防的非药物性神经轴索干预措施。

Nonpharmacologic Neuraxial Interventions for Prophylaxis of Postdural Puncture Headache in the Obstetric Patient.

作者信息

Suescun Heather, Austin Paul, Gabaldon Dion

出版信息

AANA J. 2016 Feb;84(1):15-22.

Abstract

Postdural puncture headache due to accidental dural puncture during epidural catheter placement is a source of morbidity for new mothers. It can interfere with maternal-newborn bonding and increase the length of hospitalization. This evidence-based article examined the question: For obstetric patients experiencing an accidental dural puncture during epidural placement, which nonpharmacologic prophylactic neuraxial interventions safely and effectively decrease the incidence of postdural puncture headache? A search of online databases revealed 4 systematic reviews with meta-analysis and a randomized controlled trial meeting the inclusion criteria. Three of the 4 systematic reviews used rigorous appraisal methods. Two systematic reviews included nonobstetric populations and 3 included additional interventions. Subgroup analyses allowed examination of the interventions of interest. Nonpharmacologic prophylactic neuraxial interventions included prophylactic epidural blood patch, epidural saline administration, and intrathecal catheter placement. There was a lack of standardization of interventions. The evidence suggested there may be value in performing a prophylactic blood patch or placing an intrathecal catheter. The risk of the intervention must be carefully weighed with the benefits. Further rigorous studies are needed to help determine the best methods to decrease the incidence of postdural puncture headache in obstetric patients experiencing an accidental dural puncture during epidural placement.

摘要

硬膜外导管置入过程中意外硬膜穿刺导致的硬膜穿刺后头痛是新妈妈发病的一个原因。它会干扰母婴联结并延长住院时间。这篇循证文章探讨了以下问题:对于在硬膜外穿刺过程中发生意外硬膜穿刺的产科患者,哪种非药物预防性神经轴索干预措施能安全有效地降低硬膜穿刺后头痛的发生率?对在线数据库的检索发现了4篇带有荟萃分析的系统评价和1项符合纳入标准的随机对照试验。4篇系统评价中的3篇采用了严格的评估方法。2篇系统评价纳入了非产科人群,3篇纳入了其他干预措施。亚组分析允许对感兴趣的干预措施进行审查。非药物预防性神经轴索干预措施包括预防性硬膜外血贴、硬膜外注射生理盐水和鞘内导管置入。干预措施缺乏标准化。证据表明,进行预防性血贴或置入鞘内导管可能有价值。必须仔细权衡干预措施的风险和益处。需要进一步的严格研究来帮助确定降低硬膜外穿刺过程中发生意外硬膜穿刺的产科患者硬膜穿刺后头痛发生率的最佳方法。

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