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[阳光中紫外线成分的细胞效应]

[Cellular effects of the ultraviolet components of sunlight].

作者信息

Zölzer F, Kiefer J

机构信息

Strahlenzentrum der Universität, Giessen.

出版信息

Naturwissenschaften. 1989 Nov;76(11):489-95. doi: 10.1007/BF00374120.

DOI:10.1007/BF00374120
PMID:2693973
Abstract

The discussion on the possible increase of solar UV on earth due to the destruction of the stratospheric ozone has led to a renewed interest in the action of ultraviolet radiation on biological systems. The paper deals with changes at the cellular level stressing particularly molecular alterations in deoxyribonucleic acid, the carrier of genetic information. The most important repair processes by which lesions are removed or bypassed are described. It is also discussed whether the effectivity of a complex spectrum can be predicted on the basis of measurements with monochromatic radiation. Furthermore, possible consequences on human health are outlined which may be derived from cellular studies.

摘要

关于平流层臭氧破坏可能导致地球太阳紫外线增加的讨论,引发了人们对紫外线辐射对生物系统作用的新兴趣。本文论述了细胞水平的变化,特别强调了遗传信息载体脱氧核糖核酸的分子改变。文中描述了去除或绕过损伤的最重要修复过程。还讨论了是否可以根据单色辐射的测量结果来预测复杂光谱的有效性。此外,概述了细胞研究可能对人类健康产生的后果。

相似文献

1
[Cellular effects of the ultraviolet components of sunlight].[阳光中紫外线成分的细胞效应]
Naturwissenschaften. 1989 Nov;76(11):489-95. doi: 10.1007/BF00374120.
2
The genotoxic effects of DNA lesions induced by artificial UV-radiation and sunlight.人工紫外线辐射和阳光引起的 DNA 损伤的遗传毒性效应。
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Development of a DNA-dosimeter system for monitoring the effects of solar-ultraviolet radiation.用于监测太阳紫外线辐射影响的DNA剂量计系统的开发。
Photochem Photobiol Sci. 2009 Jan;8(1):111-20. doi: 10.1039/b810085c. Epub 2008 Nov 20.
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Sunlight damage to cellular DNA: Focus on oxidatively generated lesions.阳光对细胞DNA的损伤:聚焦于氧化产生的损伤。
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6
Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light.原位紫外线照射下人皮肤DNA中嘧啶二聚体形成的波长依赖性。
Proc Natl Acad Sci U S A. 1989 Jul;86(14):5605-9. doi: 10.1073/pnas.86.14.5605.
7
Impact of solar UV radiation on amphibians: focus on genotoxic stress.太阳紫外线辐射对两栖动物的影响:聚焦于遗传毒性应激。
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The effects of the ultraviolet wavelengths of radiation present in sunlight on human cells in vitro.
Photochem Photobiol. 1987 Dec;46(6):1043-50. doi: 10.1111/j.1751-1097.1987.tb04891.x.
9
Ozone-climate interactions and effects on solar ultraviolet radiation.臭氧-气候相互作用及其对太阳紫外线辐射的影响。
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Monitoring of environmental UV radiation by biological dosimeters.利用生物剂量计监测环境紫外线辐射。
Adv Space Res. 2000;26(12):2021-8. doi: 10.1016/s0273-1177(00)00174-5.

本文引用的文献

1
A STUDY OF THE BACTERICIDAL ACTION OF ULTRA VIOLET LIGHT : III. THE ABSORPTION OF ULTRA VIOLET LIGHT BY BACTERIA.紫外线杀菌作用的研究:III. 细菌对紫外线的吸收。
J Gen Physiol. 1930 Sep 20;14(1):31-42. doi: 10.1085/jgp.14.1.31.
2
STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III.肺炎球菌型转变物质的化学性质研究:从 III 型肺炎球菌中分离出的脱氧核糖核酸片段诱导转化。
J Exp Med. 1944 Feb 1;79(2):137-58. doi: 10.1084/jem.79.2.137.
3
Erythema and melanogenesis action spectra of normal human skin.
正常人体皮肤的红斑和黑素生成作用光谱。
Photochem Photobiol. 1982 Aug;36(2):187-91. doi: 10.1111/j.1751-1097.1982.tb04362.x.
4
Dose-time dependency of tumor formation by chronic UV exposure.慢性紫外线照射导致肿瘤形成的剂量-时间依赖性。
Photochem Photobiol. 1983 Jan;37(1):53-62. doi: 10.1111/j.1751-1097.1983.tb04433.x.
5
Single-strand breaks induced in Bacillus subtilis DNA by ultraviolet light: action spectrum and properties.
Photochem Photobiol. 1982 May;35(5):675-80. doi: 10.1111/j.1751-1097.1982.tb02628.x.
6
Genetic effects of fluorescent lamp radiation on eukaryotic cells in culture.荧光灯辐射对培养的真核细胞的遗传效应。
Photochem Photobiol. 1982 Jun;35(6):875-9. doi: 10.1111/j.1751-1097.1982.tb02662.x.
7
Induction of DNA strand breaks in normal human fibroblasts exposed to monochromatic ultraviolet and visible wavelengths in the 240-546 nm range.在暴露于240-546纳米范围内单色紫外线和可见光波长的正常人成纤维细胞中诱导DNA链断裂。
Photochem Photobiol. 1983 Jul;38(1):51-5. doi: 10.1111/j.1751-1097.1983.tb08365.x.
8
Ultraviolet action spectra for DNA dimer induction, lethality, and mutagenesis in Escherichia coli with emphasis on the UVB region.
Photochem Photobiol. 1984 Nov;40(5):613-20. doi: 10.1111/j.1751-1097.1984.tb05349.x.
9
Leakage of 86Rb+ after ultraviolet irradiation of Escherichia coli K-12.
Photochem Photobiol. 1984 Mar;39(3):329-35. doi: 10.1111/j.1751-1097.1984.tb08186.x.
10
Pyrimidine dimer formation and repair in human skin.人类皮肤中嘧啶二聚体的形成与修复
Cancer Res. 1980 Sep;40(9):3181-5.