Izumi Mie, Manabe Emiko, Uematsu Sayo, Watanabe Ayako, Moritani Toshio
a Department of Nursing , Doshisha Women's College of Liberal Arts , Kyoto , Japan .
b Graduate School of Psychological Science, Hiroshima International University , Hiroshima , Japan , and.
J Psychosom Obstet Gynaecol. 2016;37(2):51-6. doi: 10.3109/0167482X.2016.1142970. Epub 2016 Mar 3.
We investigated the association between autonomic nervous system (ANS) activity and symptoms of anxiety and depression for the first 2 years postpartum.
A total of 108 participants within 2 years postpartum underwent physiological measurements of ANS activity using the heart rate variability (HRV) power spectrum and self-reported questionnaires (14-item Hospital Anxiety and Depression Score). The cutoff points for anxiety and depressive symptom scores in this questionnaire were as follows: 7 or less, non-cases; 8-10, doubtful cases; 11 or more, definite cases. This study was conducted from 2012 to 2014 at University Hospital in Kyoto Prefectural University of Medicine and a nearby obstetrics and gynecology department clinic in Japan.
Anxiety and depression non-cases accounted for 67.6% (n = 73) of subjects, anxiety non-cases and depression doubtful and definite cases 7.4% (n = 8), anxiety doubtful and definite cases and depression non-cases 8.3% (n = 9), and anxiety and depression doubtful and definite cases 16.7% (n = 18). Findings were similar for women with anxiety or depression, with total power (TP), low-frequency (LF) and high-frequency (HF) components of HRV among doubtful and definite cases significantly lower than among non-cases for both anxiety (p = 0.006, 0.034, 0.029, respectively) and depression (p = 0.001, 0.004, 0.007). Significant correlations were observed between TP, LF and HF and anxiety and depression scores (respective values for anxiety: rs = -0.331, p <0.001; rs = -0.286, p = 0.003; rs = -0.269, p = 0.005; and depression: rs = -0.389, rs = -0.353, rs = -0.337, all p <0.001).
The present study demonstrated that mothers with anxiety or depressive symptoms had significantly lower HRV (HF, LF and TP) than those without.
我们调查了产后头两年自主神经系统（ANS）活动与焦虑和抑郁症状之间的关联。
共有108名产后两年内的参与者使用心率变异性（HRV）功率谱进行了ANS活动的生理测量，并填写了自我报告问卷（14项医院焦虑抑郁量表）。该问卷中焦虑和抑郁症状评分的临界值如下：7分及以下，非病例；8 - 10分，可疑病例；11分及以上，确诊病例。本研究于2012年至2014年在日本京都府立医科大学附属医院及附近的妇产科诊所进行。
焦虑和抑郁非病例占受试者的67.6%（n = 73），焦虑非病例与抑郁可疑及确诊病例占7.4%（n = 8），焦虑可疑及确诊病例与抑郁非病例占8.3%（n = 9），焦虑和抑郁可疑及确诊病例占16.7%（n = 18）。焦虑或抑郁女性的结果相似，对于焦虑和抑郁，可疑及确诊病例的HRV总功率（TP）、低频（LF）和高频（HF）成分均显著低于非病例（焦虑时p值分别为0.006、0.034、0.029；抑郁时p值分别为0.001、0.004、0.007）。TP、LF和HF与焦虑和抑郁评分之间存在显著相关性（焦虑的相关值：rs = -0.331，p <0.001；rs = -0.286，p = 0.003；rs = -0.269，p = 0.005；抑郁的相关值：rs = -0.389，rs = -0.353，rs = -0.337，所有p <0.001）。
本研究表明，有焦虑或抑郁症状的母亲的HRV（HF、LF和TP）显著低于没有这些症状的母亲。
