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日本先天性和发育性白内障的手术疗效。

Surgical outcomes of congenital and developmental cataracts in Japan.

作者信息

Nagamoto Toshiyuki, Oshika Tetsuro, Fujikado Takashi, Ishibashi Tatsuro, Sato Miho, Kondo Mineo, Kurosaka Daijiro, Azuma Noriyuki

机构信息

Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.

Nagamoto Eye Clinic, Tokyo, Japan.

出版信息

Jpn J Ophthalmol. 2016 May;60(3):127-34. doi: 10.1007/s10384-016-0436-2. Epub 2016 Mar 3.

Abstract

PURPOSE

To retrospectively analyze the surgical outcomes of congenital/developmental cataracts in Japan.

METHODS

A mail questionnaire was sent to facilities engaged in surgical treatment of congenital cataracts.

RESULTS

Twenty-nine facilities reported on 809 eyes of 508 patients with congenital/developmental cataracts. Three hundred fifty-nine eyes underwent intraocular lens implantation (pseudophakia group), while 450 eyes were left aphakic (aphakia group). The average age at surgery was significantly higher in the pseudophakia group (70 ± 53 months) than in the aphakia group (14 ± 24 months) (P < 0.0001). A significantly larger proportion of patients with unilateral cataract (52.0 %) received IOL implantation than did those with bilateral cataracts (42.6 %) (P = 0.0224). The prevalence of associated ocular disorders, such as nystagmus, microcornea, nanophthalmos, and persistent fetal vasculature, was significantly higher in the aphakia group than in the pseudophakia group. Postoperatively, glaucoma developed more frequently in the aphakia group (5.8 %) than in the pseudophakia group (0.7 %) (P = 0.0003). Posterior capsule opacification developed more frequently in the pseudophakic eyes even when both posterior capsulotomy and anterior vitrectomy were performed, especially in patients aged 1 year or younger. Postoperative visual acuity was significantly better in the pseudophakia group than in the aphakia group, both in the unilateral and in the bilateral cases.

CONCLUSIONS

Surgeons tended to select IOL implantation, rather than to leave the eye aphakic, in patients who were older at the time of surgery, had fewer coexisting ocular disorders, and suffered from unilateral cataract. Under such circumstances, pseudophakic eyes obtained significantly better postoperative visual acuity than did aphakic eyes.

摘要

目的

回顾性分析日本先天性/发育性白内障的手术效果。

方法

向从事先天性白内障手术治疗的机构发送邮件调查问卷。

结果

29家机构报告了508例先天性/发育性白内障患者的809只眼。359只眼接受了人工晶状体植入术(假晶状体组),而450只眼为无晶状体眼(无晶状体组)。假晶状体组的平均手术年龄(70±53个月)显著高于无晶状体组(14±24个月)(P<0.0001)。单侧白内障患者接受人工晶状体植入的比例(52.0%)显著高于双侧白内障患者(42.6%)(P=0.0224)。无晶状体组中眼球震颤、小角膜、小眼球和永存原始玻璃体增生症等相关眼部疾病的患病率显著高于假晶状体组。术后,无晶状体组青光眼的发生率(5.8%)高于假晶状体组(0.7%)(P=0.0003)。即使进行了后囊切开术和前部玻璃体切除术,假晶状体眼后囊膜混浊的发生率仍更高,尤其是1岁及以下的患者。在单侧和双侧病例中,假晶状体组的术后视力均显著优于无晶状体组。

结论

对于手术时年龄较大、并存眼部疾病较少且为单侧白内障的患者,外科医生倾向于选择人工晶状体植入术,而非让眼睛保持无晶状体状态。在这种情况下,假晶状体眼的术后视力明显优于无晶状体眼。

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