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为经腭、经腭-上颌骨周围(经翼腭)及经腭-上颌骨周围-唇下入路治疗青少年鼻咽血管纤维瘤外侧扩展病变进行辩护。

In defence of transpalatal, transpalatal-circumaxillary (transpterygopalatine) and transpalatal-circumaxillary-sublabial approaches to lateral extensions of juvenile nasopharyngeal angiofibroma.

作者信息

Mishra A, Mishra S C, Verma V, Singh H P, Kumar S, Tripathi A M, Patel B, Singh V

机构信息

Department of Otorhinolaryngology,King George Medical University,Lucknow,India.

出版信息

J Laryngol Otol. 2016 May;130(5):462-73. doi: 10.1017/S0022215116000773. Epub 2016 Mar 4.

Abstract

BACKGROUND

Juvenile nasopharyngeal angiofibroma often presents with lateral extensions. In countries with limited resources, selection of a cost-effective and least morbid surgical approach for complete excision is challenging.

METHODS

Sixty-three patients with juvenile nasopharyngeal angiofibroma, with lateral extensions, underwent transpalatal, transpalatal-circumaxillary (transpterygopalatine) or transpalatal-circumaxillary-sublabial approaches for resection. Clinico-radiological characteristics, tumour volume and intra-operative bleeding were recorded.

RESULTS

The transpalatal approach was suitable for extensions involving medial part of pterygopalatine fossa; transpalatal-circumaxillary for extensions involving complete pterygopalatine fossa, with or without partial infratemporal fossa; and transpalatal-circumaxillary-sublabial for extensions involving complete infratemporal fossa, even cheek or temporal fossa up to zygomatic arch. Haemorrhage was greatest with the transpalatal-circumaxillary-sublabial approach, followed by transpalatal approach and transpalatal-circumaxillary approach (1212, 950 and 777 ml respectively). Tumour size (volume) was greatest with the transpalatal-circumaxillary approach, followed by transpalatal-circumaxillary-sublabial approach and transpalatal approach (40, 34 and 29 mm3). There was recurrence in three cases and residual disease in two cases. Long-term morbidity included small palatal perforation (n = 1), trismus (n = 1) and atrophic rhinitis (n = 2).

CONCLUSION

These modified techniques, performed with endoscopic assistance under hypotensive anaesthesia, without embolisation, offer a superior option over other open procedures with regard to morbidity and recurrences.

摘要

背景

青少年鼻咽血管纤维瘤常呈侧向扩展。在资源有限的国家,选择一种具有成本效益且创伤最小的手术方法以实现完整切除具有挑战性。

方法

63例具有侧向扩展的青少年鼻咽血管纤维瘤患者接受了经腭、经腭-环上颌(经翼腭窝)或经腭-环上颌-唇下入路进行切除。记录临床放射学特征、肿瘤体积和术中出血情况。

结果

经腭入路适用于累及翼腭窝内侧部分的扩展;经腭-环上颌入路适用于累及完整翼腭窝(无论有无部分颞下窝)的扩展;经腭-环上颌-唇下入路适用于累及完整颞下窝、甚至脸颊或直至颧弓的颞窝的扩展。经腭-环上颌-唇下入路的出血量最大,其次是经腭入路和经腭-环上颌入路(分别为1212、950和777毫升)。经腭-环上颌入路的肿瘤大小(体积)最大,其次是经腭-环上颌-唇下入路和经腭入路(分别为40、34和29立方毫米)。有3例复发,2例有残留病灶。长期并发症包括小的腭穿孔(1例)、牙关紧闭(1例)和萎缩性鼻炎(2例)。

结论

这些改良技术在降压麻醉下借助内镜进行,无需栓塞,在并发症和复发方面比其他开放手术提供了更好的选择。

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