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帕金森病伴视幻觉患者的注意力加工功能障碍。

Dysfunction in attentional processing in patients with Parkinson's disease and visual hallucinations.

作者信息

Hall Julie M, O'Callaghan Claire, Shine James M, Muller Alana J, Phillips Joseph R, Walton Courtney C, Lewis Simon J G, Moustafa Ahmed A

机构信息

Parkinson's Disease Research Clinic, Brain and Mind Centre, University of Sydney, Sydney, NSW, Australia.

School of Social Sciences and Psychology, Western Sydney University, Sydney, NSW, Australia.

出版信息

J Neural Transm (Vienna). 2016 May;123(5):503-7. doi: 10.1007/s00702-016-1528-3. Epub 2016 Mar 3.

DOI:10.1007/s00702-016-1528-3
PMID:26940598
Abstract

Mechanistic insights into visual hallucinations (VH) in Parkinson's disease (PD) have suggested a role for impaired attentional processes. The current study tested 25 PD patients with and 28 PD patients without VH on the attentional network test. Hallucinators had significantly lower accuracy rates compared to non-hallucinators, but no differences were found in reaction times. This suggests that hallucinators show deficits in attentional processes and conflict monitoring. Our findings provide novel behavioural insights that dovetail with current neurobiological frameworks of VH.

摘要

对帕金森病(PD)中视幻觉(VH)的机制性见解表明,注意力过程受损起到了一定作用。本研究对25名有视幻觉的PD患者和28名无视幻觉的PD患者进行了注意力网络测试。与无幻觉者相比,有幻觉者的准确率显著更低,但反应时间未发现差异。这表明有幻觉者在注意力过程和冲突监测方面存在缺陷。我们的研究结果提供了新的行为学见解,与当前视幻觉的神经生物学框架相契合。

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本文引用的文献

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Abnormal connectivity between the default mode and the visual system underlies the manifestation of visual hallucinations in Parkinson's disease: a task-based fMRI study.默认模式与视觉系统之间的异常连接是帕金森病视觉幻觉表现的基础:一项基于任务的功能磁共振成像研究。
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Visual hallucinations in Parkinson's disease: theoretical models.帕金森病中的视幻觉:理论模型
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The default mode network is disrupted in Parkinson's disease with visual hallucinations.
与帕金森病精神病相关的功能和连接相关性:一项系统综述。
Brain Commun. 2024 Nov 6;6(6):fcae358. doi: 10.1093/braincomms/fcae358. eCollection 2024.
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Pareidolia in Schizophrenia and Bipolar Disorder.精神分裂症和双相情感障碍中的空想性错视。
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Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies.在路易体痴呆症中,即使在豆状核无严重病理学改变的情况下,也存在分子变化。
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Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies.路易体痴呆与帕金森病痴呆:当前的概念和争议。
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默认模式网络在伴有视幻觉的帕金森病中会受到干扰。
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Tricks of the mind: Visual hallucinations as disorders of attention.思维的技巧:视觉幻觉作为注意力障碍。
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Visuoperceptive region atrophy independent of cognitive status in patients with Parkinson's disease with hallucinations.帕金森病伴幻觉患者的视知觉区域萎缩与认知状态无关。
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Visual misperceptions and hallucinations in Parkinson's disease: dysfunction of attentional control networks?帕金森病中的视觉错觉和幻觉:注意力控制网络的功能障碍?
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Utilising functional MRI (fMRI) to explore the freezing phenomenon in Parkinson's disease.利用功能磁共振成像(fMRI)探索帕金森病中的冻结现象。
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[Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS): a new scale for the evaluation of Parkinson's disease].[运动障碍协会统一帕金森病评定量表(MDS-UPDRS):一种评估帕金森病的新量表]
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