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癌症患儿化疗端口的并发症:来自印度南部一家三级癌症中心54100导管日的经验。

Complications of chemoport in children with cancer: Experience of 54,100 catheter days from a tertiary cancer center of Southern India.

作者信息

Aparna S, Ramesh S, Appaji L, Srivatsa Kavitha, Shankar Gowri, Jadhav Vinay, Babu Narendra

机构信息

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India.

Department of Pediatric Surgery, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India.

出版信息

South Asian J Cancer. 2015 Jul-Sep;4(3):143-5. doi: 10.4103/2278-330X.173179.

Abstract

BACKGROUND

Chemoport is an essential part of the management of children with cancer and provides long-term venous access. There are few studies from resource poor countries reporting complications of chemoport.

AIMS

This study was aimed at describing the complications of chemoport in patients with cancer.

MATERIALS AND METHODS

This retrospective observational study analyzed 200 patients <15 years of age who underwent chemoport insertion. The medical records of these patients were reviewed for the patient characteristics, diagnosis, nature of port use, port-related complications and their management.

RESULTS

A total of 209 ports were implanted in 200 patients and 24 ports were removed due to port-related complications. There were 122 boys and 78 girls whose ages ranged from 4 months to 13 years (median age 2.5 years). About72% of patients were <2 years old. The cumulative duration of catheterization was 54,100 days. Of 209 ports, there were 36 complications that led to the removal of 21 ports. Port-related infection was the most common infection observed in our study (0.66/1000 catheter days and 11.9%). Mechanical complications were seen in 9 patients. Venous thrombosis and skin necrosis occurred in one patient each.

CONCLUSIONS

Use of chemoport is safe and is a boon for children with cancer in developing countries with incidence of complications similar to Western countries. Although use of chemoport is associated with complications, they are easily managed. With stringent catheter care by trained personnel, some complications can be prevented.

摘要

背景

化疗端口是儿童癌症治疗的重要组成部分,可提供长期静脉通路。资源匮乏国家关于化疗端口并发症的研究较少。

目的

本研究旨在描述癌症患者化疗端口的并发症。

材料与方法

这项回顾性观察研究分析了200例15岁以下接受化疗端口植入的患者。对这些患者的病历进行回顾,以了解患者特征、诊断、端口使用性质、与端口相关的并发症及其处理情况。

结果

200例患者共植入209个端口,24个端口因与端口相关的并发症而被拔除。其中男孩122例,女孩78例,年龄从4个月至13岁(中位年龄2.5岁)。约72%的患者年龄小于2岁。导管插入的累计时长为54100天。在209个端口中,有36例并发症导致21个端口被拔除。与端口相关的感染是本研究中观察到的最常见感染(0.66/1000导管日,发生率为11.9%)。9例患者出现机械性并发症。静脉血栓形成和皮肤坏死各发生1例。

结论

化疗端口的使用是安全的,对于发展中国家的癌症儿童来说是一项福音,其并发症发生率与西方国家相似。虽然化疗端口的使用会引发并发症,但这些并发症易于处理。通过训练有素的人员进行严格的导管护理,一些并发症是可以预防的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3602/4756491/19bc9089995b/SAJC-4-143-g002.jpg

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