Arneberg P, Storhaug K, Sandvik L
Department of Cariology, Dental Faculty, Oslo, Norway.
Scand J Dent Res. 1989 Oct;97(5):408-14. doi: 10.1111/j.1600-0722.1989.tb01454.x.
A motion sickness plaster releasing a powerful antisialogogic agent, scopolamine, was tested in a double blind clinical trial for its effect on salivary parameters in 14 healthy young men. The agent caused a decline in salivary flow rates, which was most pronounced during unstimulated conditions. Salivary pH and buffer capacity were also reduced. Salivary levels of Streptococcus mutans and lactobacilli showed a tendency to increase during 2 days on the antisialogogic agent, but the effect on S. mutans levels was not statistically significant.
一种释放强效抗涎剂东莨菪碱的晕动病贴剂，在一项双盲临床试验中对14名健康年轻男性的唾液参数影响进行了测试。该药物导致唾液流速下降，在非刺激状态下最为明显。唾液pH值和缓冲能力也有所降低。在使用抗涎剂的2天里，变形链球菌和乳酸杆菌的唾液水平有增加趋势，但对变形链球菌水平的影响无统计学意义。
