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巨大肝血管瘤伴卡萨巴赫-梅里特综合征导致的梗阻性黄疸:一例报告

Obstructive jaundice caused by a giant liver hemangioma with Kasabach-Merritt syndrome: a case report.

作者信息

Yano Takuya, Kobayashi Tsuyoshi, Kuroda Shintaro, Amano Hironobu, Tashiro Hirotaka, Ohdan Hideki

机构信息

Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

出版信息

Surg Case Rep. 2015 Dec;1(1):93. doi: 10.1186/s40792-015-0095-4. Epub 2015 Oct 6.

Abstract

Hemangioma is the most common benign tumor of the liver. Liver hemangioma (LH) usually remains asymptomatic, but the most common symptoms associated with LH are abdominal pain and discomfort. LH is an uncommon cause of bile duct dilatation and obstructive jaundice. An 83-year-old Japanese woman who received hemodialysis at another hospital was referred to our hospital because of abnormal liver function and obstructive jaundice. Abdominal computed tomography and magnetic resonance imaging revealed a 13-cm tumor in liver segments IV-V and intrahepatic bile duct dilatation. Endoscopic retrograde cholangiopancreatography revealed extrinsic compression of the bile duct at the hepatic hilar region. Laboratory tests showed that the patient had low platelet counts and low fibrinogen levels. Because the patient had hyperbilirubinemia and Kasabach-Merritt syndrome, we performed a segmentectomy of liver segments IV and V. Histological examination showed hemangioma of the liver. The patient's thrombocytopenia and coagulopathy improved immediately after surgery. In conclusion, LH is a very rare cause of obstructive jaundice. LH has the potential to compress the bile duct and cause obstructive jaundice.

摘要

肝血管瘤是肝脏最常见的良性肿瘤。肝血管瘤(LH)通常无症状,但与LH相关的最常见症状是腹痛和不适。LH是胆管扩张和梗阻性黄疸的罕见原因。一名83岁在另一家医院接受血液透析的日本女性因肝功能异常和梗阻性黄疸被转诊至我院。腹部计算机断层扫描和磁共振成像显示肝IV - V段有一个13厘米的肿瘤以及肝内胆管扩张。内镜逆行胰胆管造影显示肝门区胆管受到外在压迫。实验室检查表明该患者血小板计数低且纤维蛋白原水平低。由于患者有高胆红素血症和卡萨巴切 - 梅里特综合征,我们对肝IV段和V段进行了肝段切除术。组织学检查显示为肝脏血管瘤。患者的血小板减少症和凝血病在手术后立即得到改善。总之,LH是梗阻性黄疸的非常罕见的原因。LH有可能压迫胆管并导致梗阻性黄疸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d3e/4595412/13fbb5263efe/40792_2015_95_Fig1_HTML.jpg

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