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采用改良结肠后-结肠上入路的腹腔镜Roux-en-Y胃旁路手术:300例患者的手术结果

Laparoscopic Roux en-Y Gastric Bypass Using a Modified Retrocolic-Supracolic Approach: Outcomes from 300 Patients.

作者信息

Al-Khyatt Waleed, Bull Charles A, Awad Sherif, Ahmed Javed

机构信息

The East-Midlands Bariatric & Metabolic Institute (EMBMI), Royal Derby Hospital, Uttoxeter Road, Derby, DE22 3NE, UK.

出版信息

World J Surg. 2016 Aug;40(8):1918-24. doi: 10.1007/s00268-016-3478-1.

Abstract

BACKGROUND

Laparoscopic Roux en-Y gastric bypass (LRYGB) achieves sustained long-term weight loss and reduced mortality in morbidly obese patients. It is routinely performed using an ante- or retrocolic approach with the jejuno-jejunostomy constructed in the infracolic compartment. We have modified the standard technique of performing LRYGB by constructing both anastomoses in the supracolic compartment. This study describes the outcomes of consecutive primary LRYGB performed using this novel retrocolic-supracolic approach.

METHODS

Data were prospectively collected on consecutive primary LRYGB performed in a tertiary-referral Bariatric Centre in the United Kingdom from September 2009 to March 2013. Data included demographics, operative outcomes (duration of surgery, postoperative anastomotic leak/bleeding/reoperations), development of strictures, length of stay, excess weight loss (EWL) and resolution of diabetes mellitus.

RESULTS

Hand-sewn LRYGB was successfully performed using the retrocolic-supracolic approach in 300 of 307 (98 %) consecutive patients (72 % female). Median (IQR) age, weight and baseline body mass index were 49 (41-56) years, 146 (134-163) kg and 52.9 (48.8-57.2) kg/m(2), respectively. There were 4 (1.3 %) anastomotic leaks and 8 (2.6 %) postoperative bleeds. The 30-day reoperation rate was 1.6 %. Median (IQR) hospital stay was 2 (2-2) days. Postoperative dysphagia requiring endoscopic balloon dilatation occurred in 19 (6.3 %) patients. Mean ± SD 12-month EWL was 69.9 ± 19.0 %. Within the follow-up period, 81 % of patients with type II diabetes mellitus achieved remission and 19 % reduced dosage of diabetes medication.

CONCLUSIONS

LRYGB performed using the retrocolic-supracolic approach was safe, feasible, technically advantageous and resulted in clinical outcomes akin to the standard infracolic approach.

摘要

背景

腹腔镜Roux-en-Y胃旁路手术(LRYGB)可使病态肥胖患者实现长期持续减重并降低死亡率。该手术通常采用结肠前或结肠后入路,空肠吻合术在结肠下区进行。我们通过在结肠上区构建两个吻合口,对LRYGB的标准手术技术进行了改良。本研究描述了采用这种新型结肠后 - 结肠上入路连续进行的原发性LRYGB的手术结果。

方法

前瞻性收集了2009年9月至2013年3月在英国一家三级转诊肥胖症治疗中心连续进行的原发性LRYGB手术数据。数据包括人口统计学资料、手术结果(手术时长、术后吻合口漏/出血/再次手术情况)、狭窄的发生情况、住院时间、超重减轻量(EWL)以及糖尿病缓解情况。

结果

在307例连续患者中的300例(98%)成功采用结肠后 - 结肠上入路进行了手工缝合的LRYGB手术(72%为女性)。年龄、体重和基线体重指数的中位数(四分位间距)分别为49(41 - 56)岁、146(134 - 163)千克和52.9(48.8 - 57.2)千克/平方米。发生了4例(1.3%)吻合口漏和8例(2.6%)术后出血。30天再次手术率为1.6%。住院时间中位数(四分位间距)为2(2 - 2)天。19例(6.3%)患者发生术后吞咽困难,需要内镜下球囊扩张。12个月时平均±标准差的EWL为69.9±19.0%。在随访期内,81%的II型糖尿病患者实现缓解,19%的患者减少了糖尿病药物剂量。

结论

采用结肠后 - 结肠上入路进行的LRYGB手术安全、可行,具有技术优势,且临床结果与标准结肠下入路相似。

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