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腹腔镜胃旁路术治疗病态肥胖——一项比较两种胃空肠吻合技术的随机对照试验

Laparoscopic gastric bypass for morbid obesity-a randomized controlled trial comparing two gastrojejunal anastomosis techniques.

作者信息

Leyba Jose Luis, Llopis Salvador Navarrete, Isaac Jose, Aulestia Salvador Navarrete, Bravo Carlos, Obregon Francisco

机构信息

Universidad Central de Venezuela, Caracus, Venezuela.

出版信息

JSLS. 2008 Oct-Dec;12(4):385-8.

Abstract

OBJECTIVES

We present a randomized controlled trial of laparoscopic gastric bypass comparing 2 techniques of gastrojejunostomy in patients with morbid obesity.

METHODS

Eighty consecutive patients underwent laparoscopic Roux-en-Y gastric bypass between September 2005 and August 2006. Patients were randomly assigned to 2 groups by the use of sealed envelopes. In group A, the gastrojejunal anastomosis was performed with a 21-mm circular-stapler, and in group B, this anastomosis was performed with a 45-mm linear-stapler. The rest of the procedure was identical in both groups. Variables evaluated were complications involving the gastrojejunostomy, operative time, length of stay, and percentage of excess weight loss.

RESULTS

Both groups were similar in age and body mass index. No patients experienced leakage or gastrojejunal anastomosis fistula, but group A patients had a more frequent stricture rate (P<0.05). Operative time and hospital stay were comparable in both groups (P>0.05). Percentage excess weight loss at one year following surgery was satisfactory in both groups, without a statistically significant difference (P>0.05).

CONCLUSION

Gastrojejunal anastomosis does not seem to be a critical factor in excess weight loss for morbidly obese patients who underwent laparoscopic gastric bypass. The 2 techniques used in this experience are safe and effective; however, the 45-mm liner-stapler is preferable because it has a lower stricture rate.

摘要

目的

我们开展了一项腹腔镜胃旁路手术的随机对照试验,比较病态肥胖患者两种胃空肠吻合技术。

方法

2005年9月至2006年8月期间,连续80例患者接受了腹腔镜Roux-en-Y胃旁路手术。通过使用密封信封将患者随机分为两组。A组使用21毫米圆形吻合器进行胃空肠吻合,B组使用45毫米线性吻合器进行该吻合。两组的其余手术步骤相同。评估的变量包括涉及胃空肠吻合的并发症、手术时间、住院时间和超重减轻百分比。

结果

两组在年龄和体重指数方面相似。没有患者出现渗漏或胃空肠吻合口瘘,但A组患者的狭窄发生率更高(P<0.05)。两组的手术时间和住院时间相当(P>0.05)。两组术后一年的超重减轻百分比均令人满意,无统计学显著差异(P>0.05)。

结论

对于接受腹腔镜胃旁路手术的病态肥胖患者,胃空肠吻合似乎不是超重减轻的关键因素。本研究中使用的两种技术安全有效;然而,45毫米线性吻合器更可取,因为其狭窄发生率较低。

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