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用于复杂经皮冠状动脉介入治疗的自膨胀支架:真实病例经验

Self-expanding stent for complex percutaneous coronary interventions: A real life experience.

作者信息

Pastormerlo Luigi Emilio, Ciardetti Marco, Coceani Michele, Trianni Giuseppe, Ravani Marcello, Vaghetti Marco, Rizza Antonio, De Caterina Alberto, Berti Sergio, Palmieri Cataldo

机构信息

Division of Interventional Cardiology, Fondazione G. Monasterio CNR-Regione Toscana, Pisa-Massa, Italy; Life Sciences Institute - Scuola Superiore Sant'Anna, Pisa, Italy.

Division of Interventional Cardiology, Fondazione G. Monasterio CNR-Regione Toscana, Pisa-Massa, Italy.

出版信息

Cardiovasc Revasc Med. 2016 Apr-May;17(3):186-9. doi: 10.1016/j.carrev.2016.02.005. Epub 2016 Feb 12.

Abstract

AIM

Self-expanding stents represent a re-emerging option for percutaneous coronary interventions. Their application covers a wide spectrum of angiographic situations, i.e., coronary bifurcations, acute coronary syndromes with large thrombotic burden and stenosis of ectatic coronaries. We review our experience with self-expanding stents for different clinical and angiographic indications, with long clinical follow-up.

METHODS

From 2011 to 2013 we used self-expanding STENTYS® stents in 40 consecutive patients followed-up for death from any cause and from cardiovascular cause, myocardial infarction, target lesion revascularization (TLR), stent thrombosis (mean 21±13months). We also revised rate of procedural outcomes, acute stent thrombosis and TLR in patients treated with conventional stents for similar clinical/angiographic situations, in the same period at our institution.

RESULTS

We identified three anatomical settings of STENTYS® use: coronary bifurcations with proximal/distal main branch diameter discrepancy (55% of cases), massive thrombotic burden in the setting of acute coronary syndrome (35% of cases) and stenosis of ectatic coronaries (15%). We observed one death related to acute heart failure and 1 case (2.5%) of acute stent thrombosis (2.5% in the control group). During follow-up 2 cases of stent restenosis leading to TLR (5%) occurred (6.25% in the control group).

CONCLUSIONS

According to our real life experience, self-expanding STENTYS® stents appear to be an effective tool for different angiographic situations in which they may be preferable to balloon-expandable stents, showing a low rate of complications and good results at long term follow-up.

摘要

目的

自膨胀支架是经皮冠状动脉介入治疗中重新出现的一种选择。其应用涵盖了广泛的血管造影情况,即冠状动脉分叉、血栓负荷大的急性冠状动脉综合征以及扩张型冠状动脉狭窄。我们回顾了在不同临床和血管造影适应证下使用自膨胀支架的经验,并进行了长期临床随访。

方法

2011年至2013年,我们连续对40例患者使用了自膨胀STENTYS®支架,并随访任何原因导致的死亡、心血管原因导致的死亡、心肌梗死、靶病变血运重建(TLR)、支架血栓形成情况(平均随访21±13个月)。我们还回顾了同期在本机构中针对类似临床/血管造影情况使用传统支架治疗的患者的手术结果、急性支架血栓形成和TLR发生率。

结果

我们确定了使用STENTYS®支架的三种解剖学情况:近端/远端主支直径存在差异的冠状动脉分叉(55%的病例)、急性冠状动脉综合征伴有大量血栓负荷(35%的病例)以及扩张型冠状动脉狭窄(15%)。我们观察到1例与急性心力衰竭相关的死亡以及1例(2.5%)急性支架血栓形成(对照组为2.5%)。在随访期间,发生了2例导致TLR的支架再狭窄(5%)(对照组为6.25%)。

结论

根据我们的实际经验,自膨胀STENTYS®支架似乎是一种适用于不同血管造影情况的有效工具,在这些情况下它可能比球囊扩张支架更具优势,并发症发生率低,长期随访效果良好。

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