Pastormerlo Luigi Emilio, Ciardetti Marco, Coceani Michele, Trianni Giuseppe, Ravani Marcello, Vaghetti Marco, Rizza Antonio, De Caterina Alberto, Berti Sergio, Palmieri Cataldo
Division of Interventional Cardiology, Fondazione G. Monasterio CNR-Regione Toscana, Pisa-Massa, Italy; Life Sciences Institute - Scuola Superiore Sant'Anna, Pisa, Italy.
Division of Interventional Cardiology, Fondazione G. Monasterio CNR-Regione Toscana, Pisa-Massa, Italy.
Cardiovasc Revasc Med. 2016 Apr-May;17(3):186-9. doi: 10.1016/j.carrev.2016.02.005. Epub 2016 Feb 12.
Self-expanding stents represent a re-emerging option for percutaneous coronary interventions. Their application covers a wide spectrum of angiographic situations, i.e., coronary bifurcations, acute coronary syndromes with large thrombotic burden and stenosis of ectatic coronaries. We review our experience with self-expanding stents for different clinical and angiographic indications, with long clinical follow-up.
From 2011 to 2013 we used self-expanding STENTYS® stents in 40 consecutive patients followed-up for death from any cause and from cardiovascular cause, myocardial infarction, target lesion revascularization (TLR), stent thrombosis (mean 21±13months). We also revised rate of procedural outcomes, acute stent thrombosis and TLR in patients treated with conventional stents for similar clinical/angiographic situations, in the same period at our institution.
We identified three anatomical settings of STENTYS® use: coronary bifurcations with proximal/distal main branch diameter discrepancy (55% of cases), massive thrombotic burden in the setting of acute coronary syndrome (35% of cases) and stenosis of ectatic coronaries (15%). We observed one death related to acute heart failure and 1 case (2.5%) of acute stent thrombosis (2.5% in the control group). During follow-up 2 cases of stent restenosis leading to TLR (5%) occurred (6.25% in the control group).
According to our real life experience, self-expanding STENTYS® stents appear to be an effective tool for different angiographic situations in which they may be preferable to balloon-expandable stents, showing a low rate of complications and good results at long term follow-up.
自膨胀支架是经皮冠状动脉介入治疗中重新出现的一种选择。其应用涵盖了广泛的血管造影情况,即冠状动脉分叉、血栓负荷大的急性冠状动脉综合征以及扩张型冠状动脉狭窄。我们回顾了在不同临床和血管造影适应证下使用自膨胀支架的经验,并进行了长期临床随访。
2011年至2013年,我们连续对40例患者使用了自膨胀STENTYS®支架,并随访任何原因导致的死亡、心血管原因导致的死亡、心肌梗死、靶病变血运重建(TLR)、支架血栓形成情况(平均随访21±13个月)。我们还回顾了同期在本机构中针对类似临床/血管造影情况使用传统支架治疗的患者的手术结果、急性支架血栓形成和TLR发生率。
我们确定了使用STENTYS®支架的三种解剖学情况:近端/远端主支直径存在差异的冠状动脉分叉(55%的病例)、急性冠状动脉综合征伴有大量血栓负荷(35%的病例)以及扩张型冠状动脉狭窄(15%)。我们观察到1例与急性心力衰竭相关的死亡以及1例(2.5%)急性支架血栓形成(对照组为2.5%)。在随访期间,发生了2例导致TLR的支架再狭窄(5%)(对照组为6.25%)。
根据我们的实际经验,自膨胀STENTYS®支架似乎是一种适用于不同血管造影情况的有效工具,在这些情况下它可能比球囊扩张支架更具优势,并发症发生率低,长期随访效果良好。